Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 213,645	$ 101,136
Marketable securities	211,093	53,153
Collaboration receivable	0	300,000
Prepaid expenses and other current assets	5,086	5,273
Total current assets	429,824	459,562
Property and equipment, net	16,943	17,563
Restricted cash	1,733	1,733
Other assets	2,403	2,400
Operating lease right-of-use assets	37,402	38,516
Total assets	488,305	519,774
Current liabilities:
Accounts payable	5,071	3,819
Accrued expenses and other current liabilities	7,010	9,562
Operating lease liabilities	6,103	6,994
Deferred revenue	30,059	28,317
Total current liabilities	48,243	48,692
Operating lease liabilities, net of current portion	50,477	51,338
Deferred revenue, net of current portion	317,068	322,730
Other liabilities	116	143
Total liabilities	415,904	422,903
Commitments and contingencies (Note 9)
Stockholders’ equity:
Preferred stock, $0.0001 par value; 25,000,000 shares authorized at March 31, 2022 and December 31, 2021; no shares issued and outstanding at March 31, 2022 and December 31, 2021	0	0
Common stock, $0.0001 par value; 175,000,000 shares authorized at March 31, 2022 and December 31, 2021; 41,429,615 shares issued and outstanding at March 31, 2022 and 41,299,720 shares issued and outstanding at December 31, 2021	4	4
Additional paid-in capital	364,761	361,133
Accumulated other comprehensive loss	(1,194)	(10)
Accumulated deficit	(291,170)	(264,256)
Total stockholders’ equity	72,401	96,871
Total liabilities and stockholders’ equity	$ 488,305	$ 519,774