Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Income Statement [Abstract]
Collaboration revenue	$ 1,319	$ 430
Operating expenses:
Research and development	80,325	57,715
General and administrative	21,728	11,246
Total operating expenses	102,053	68,961
Loss from operations	(100,734)	(68,531)
Other income (expense):
Interest expense	(1,906)	(979)
Interest income and other income (expense), net	2,553	1,001
Change in fair value of preferred stock warrant liability	0	(69)
Loss on debt extinguishment	(1,233)	(222)
Total other expense, net	(586)	(269)
Net loss	$ (101,320)	$ (68,800)
Net loss per share attributable to common stockholders—basic (in dollars per share)	$ (2.73)	$ (6.23)
Net loss per share attributable to common stockholders—diluted (in dollars per share)	$ (2.73)	$ (6.23)
Weighted average common shares outstanding—basic (in shares)	37,171,147	11,046,802
Weighted average common shares outstanding—diluted (in shares)	37,171,147	11,046,802
Comprehensive loss:
Net loss	$ (101,320)	$ (68,800)
Other comprehensive loss:
Unrealized losses on marketable securities	(3)	(7)
Total other comprehensive loss	(3)	(7)
Total comprehensive loss	$ (101,323)	$ (68,807)