Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Revenue
Collaboration revenue	$ 4,252	$ 1,947	$ 10,300	$ 7,609
Operating expenses:
Research and development	8,280	16,645	31,775	50,381
General and administrative	4,395	5,041	14,461	15,572
Total operating expenses	12,675	21,686	46,236	65,953
Loss from operations	(8,423)	(19,739)	(35,936)	(58,344)
Other income (expense), net:
Interest income	300	56	542	212
Interest expense	(606)	(499)	(1,640)	(1,481)
Other income	58	26	158	47
Total other expense, net	(248)	(417)	(940)	(1,222)
Net loss attributable to ordinary shareholders	$ (8,671)	$ (20,156)	$ (36,876)	$ (59,566)
Net loss per share attributable to common stockholders-basic (in dollars per share)	$ (0.27)	$ (0.63)	$ (1.14)	$ (1.88)
Net loss per share attributable to common stockholders-diluted (in dollars per share)	$ (0.27)	$ (0.63)	$ (1.14)	$ (1.88)
Weighted average common stock outstanding-basic (in shares)	32,399,855	32,055,551	32,389,771	31,707,068
Weighted average common stock outstanding-diluted (in shares)	32,399,855	32,055,551	32,389,771	31,707,068
Other comprehensive loss
Unrealized loss on marketable debt securities	$ (80)		$ (626)
Total other comprehensive loss	(80)		(626)
Total comprehensive loss	$ (8,751)	$ (20,156)	$ (37,502)	$ (59,566)