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Nature of the Business and Basis of Presentation (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Sep. 30, 2022
Sep. 30, 2021
Dec. 31, 2021
Nature of the Business and Basis of Presentation                  
Net loss $ 8,671 $ 14,346 $ 13,859 $ 20,156 $ 20,437 $ 18,973 $ 36,876 $ 59,566 $ 77,300
Accumulated deficit 250,115           250,115   $ 213,239
Cash, cash equivalents and marketable securities $ 78,300           $ 78,300