Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenue
Collaboration revenue (inclusive of 2,883, 6,044, $2,662 and $5,606 from a related party for the three and six months ended June 30, 2022 and 2021, respectively)	$ 2,883	$ 2,704	$ 6,048	$ 5,662
Operating expenses:
Research and development	11,877	17,751	23,495	33,736
General and administrative	5,042	4,992	10,066	10,532
Total operating expenses	16,919	22,743	33,561	44,268
Loss from operations	(14,036)	(20,039)	(27,513)	(38,606)
Other income (expense), net:
Interest income	178	71	242	157
Interest expense	(543)	(494)	(1,034)	(982)
Other income	55	25	100	21
Total other expense, net	(310)	(398)	(692)	(804)
Net loss attributable to ordinary shareholders	$ (14,346)	$ (20,437)	$ (28,205)	$ (39,410)
Net loss per share attributable to common stockholders-basic (in dollars per share)	$ (0.44)	$ (0.65)	$ (0.87)	$ (1.25)
Net loss per share attributable to common stockholders-diluted (in dollars per share)	$ (0.44)	$ (0.65)	$ (0.87)	$ (1.25)
Weighted average common stock outstanding-basic (in shares)	32,399,257	31,571,704	32,380,128	31,529,939
Weighted average common stock outstanding-diluted (in shares)	32,399,257	31,571,704	32,380,128	31,529,939
Other comprehensive loss
Unrealized loss on marketable debt securities	$ (167)		$ (546)
Total other comprehensive loss	(167)		(546)
Total comprehensive loss	$ (14,513)	$ (20,437)	$ (28,751)	$ (39,410)