X0306 4 2022-11-23 0 0001820190 Scilex Holding Company/DE SCLX 0000850261 Sorrento Therapeutics, Inc. 4955 DIRECTORS PLACE SAN DIEGO CA 94303 0 0 1 0 Warrants to Purchase Common Stock 11.50 2022-11-23 4 P 0 442829 0.3967 A 2022-11-10 2027-11-10 Common Stock 442829 4219604 D The price reported in Column 8 is a weighted average price. These warrants were purchased in multiple transactions at prices ranging from $0.2444 to $0.45 per warrant, inclusive. The Reporting Person undertakes to provide upon request to the staff of the Securities and Exchange Commission, the Issuer or a securityholder of the Issuer, full information regarding the number of warrants purchased at each separate price. /s/ Henry Ji, Ph.D., President, Chief Executive Officer and Chairman of the Board, Sorrento Therapeutics, Inc. 2022-11-23