144 0001894038 XXXXXXXX LIVE 0001819133 TANGO THERAPEUTICS, INC. 001-39485 201 BROOKLINE AVE., SUITE 901 BOSTON MA 02215 (857) 320-4900 Nextech Crossover I SCSp Former Affiliate Common Stock Goldman Sachs & Co. LLC

200 West Street New York NY 10282

3766081 113359038 144647982 06/17/2026 Nasdaq Stock Market Common Stock 08/11/2023 Private Placement Issuer N 2033980 08/11/2023 Cash Common Stock 10/24/2025 Private Placement Issuer N 1732101 10/24/2025 Cash N NEXTECH CROSSOVER I SCSP

Bahnhofstrasse 18 Zurich V8 8001

Common Stock 06/11/2026 500000 15018000 NEXTECH CROSSOVER I SCSP

Bahnhofstrasse 18 Zurich V8 8001

Common Stock 06/12/2026 500000 14870050 NEXTECH CROSSOVER I SCSP

Bahnhofstrasse 18 Zurich V8 8001

Common Stock 06/15/2026 2500000 75164250 06/17/2026 /s/ Kanishka Pothula, Managing Partner