X0206 3 2021-08-10 0 0001819133 Tango Therapeutics, Inc. TNGX 0001877364 Huang Alan C/O TANGO THERAPEUTICS, INC. 100 BINNEY STREET, SUITE 700 CAMBRIDGE MA 02142 0 1 0 0 Chief Scientific Officer Common Stock 135887 D Stock Option (Right to Buy) 1.383 2028-04-11 Common Stock 84930 D Stock Option (Right to Buy) 1.383 2028-04-11 Common Stock 110409 D Stock Option (Right to Buy) 1.531 2029-01-24 Common Stock 67944 D Stock Option (Right to Buy) 1.648 2030-01-30 Common Stock 67944 D Stock Option (Right to Buy) 3.503 2031-01-28 Common Stock 95121 D Stock Option (Right to Buy) 3.503 2031-01-28 Common Stock 67944 D This option shall vest and become exercisable in equally monthly installments over a period of 48 months from January 1, 2018. This option shall vest and become exercisable in monthly installments over a period of 48 months from April 1, 2018. This option shall vest and become exercisable over a four-year period, at a rate of 25% on January 1, 2020, with the remaining option shares vesting in 36 equal monthly installments thereafter. This option shall vest and become exercisable over a four-year period, at a rate of 25% on January 1, 2021, with the remaining option shares vesting in 36 equal monthly installments thereafter. This option shall vest and become exercisable over a four-year period, at a rate of 25% on January 1, 2022, with the remaining option shares vesting in 36 equal monthly installments thereafter. This option shall vest and become exercisable over a four-year period, at a rate of 25% on January 1, 2022, with the remaining option shares vesting in 36 equal monthly installments thereafter. Exhibit 24: Power of Attorney By: /s/ Daniella Beckman, as attorney-in-fact 2021-08-12