X0407 4 2023-05-31 0 0001757898 STERIS plc STE 0001819129 Madsen Julia C/O 70 SIR JOHN ROGERSON'S QUAY DUBLIN L2 2 IRELAND 0 1 0 0 Senior VP, Life Sciences 0 Ordinary Shares 2023-05-31 4 F 0 32 199.97 D 7278 D Ordinary Shares 2023-05-31 4 A 0 1734 0.00 A 9012 D Employee Stock Options (right to buy) 219.97 2023-05-31 4 A 0 9740 0.00 A 2033-05-31 Ordinary Shares 9740 9740 D 32 shares were withheld from the 92 restricted shares that vested on May 31, 2023. These 32 shares represent the value of the taxes required to be withheld pursuant to applicable employment or tax laws, as determined by the Issuer. These 92 ordinary shares were awarded to Ms. Madsen on May 31, 2019. These vested shares were valued at the NYSE closing market price on May 31, 2023. As of May 31, 2023, 5,598 of these ordinary shares are restricted. The restrictions on these ordinary shares lapse as follows: 123 on June 1, 2023; 352 on June 2, 2023; 360 on June 2, 2023; 349 on October 2, 2023; 144 on October 2, 2023; 578 on May 31, 2024; 352 on June 3, 2024; 123 on June 3, 2024; 360 on June 3, 2024; 349 on October 1, 2024; 144 on October 1, 2024; 578 on June 2, 2025; 352 on June 2, 2025; 360 on June 2, 2025; 144 on October 1, 2025; 578 on June 1, 2026 and 352 on June 2, 2026. This option becomes exercisable as follows: 2,435 on May 31, 2024; 2,435 on June 2, 2025; 2,435 on June 1, 2026 and 2,435 on June 1, 2027. /s/ Ronald E. Snyder, Authorized Representative under Power of Attorney 2023-06-02