X0202 SCHEDULE 13G 0002042077 XXXXXXXX LIVE Ordinary shares, par value US$0.0001 per share 03/16/2026 0001818838 Adagene Inc. 005329107 4F, BUILDING C14, NO. 218, XINGHU STREET SUZHOU INDUSTRIAL PARK JIANGSU F4 00000 Rule 13d-1(c) Chernett Jorey X1 2389060.00 0.00 2389060.00 0.00 2389060.00 N 5.1 IN Represents Ordinary Shares held by the Reporting Person. There is no CUSIP number assigned to the Ordinary Shares. CUSIP number 005329107 has been assigned to the ADSs of the Issuer, which are quoted on NASDAQ Stock Market under the symbol “ADAG.” Each ADS represents one and one quarter Ordinary Share. Adagene Inc. 4F, BUILDING C14, NO. 218, XINGHU STREET, SUZHOU INDUSTRIAL PARK, JIANGSU, CHINA, 00000 Jorey Chernett (the "Reporting Person") The principal business address of the Reporting Person is 6222 Indianwood Trail, Bloomfield Hills, MI 48301. US. Y As of the close of business on March 17, 2026, the Reporting Person beneficially owned 2,389,060 Ordinary shares, par value US$0.0001 per share, of the Issuer (the "Shares"). The aggregate percentage of Shares owned by the Reporting Person is based upon is based upon 58,914,087 of the Issuer's Ordinary Shares outstanding as of June 30, 2025, as set forth in the Issuer's Prospectus filed with the Securities and Exchange Commission on January 9, 2026. As of the close of business on March 17, 2026, the Reporting Person may be deemed to beneficially own 5.1% of the outstanding Shares. See Cover Pages Items 5-9. See Cover Pages Items 5-9. See Cover Pages Items 5-9. See Cover Pages Items 5-9. Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Chernett Jorey /s/ Jorey Chernett 03/18/2026