Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Operating expenses:
Research and development	$ 142,760	$ 121,308
General and administrative	28,202	28,717
Total operating expenses	170,962	150,025
Loss from operations	(170,962)	(150,025)
Other (expense) income:
Interest income	2,917	742
Other income (expense), net	(54)	(8)
Total other (expense) income, net	2,863	734
Net loss	$ (168,099)	$ (149,291)
Net loss per share, basic and diluted	$ (3.23)	$ (2.93)
Net loss per share, basic and diluted	$ (3.23)	$ (2.93)
Weighted average common shares outstanding, basic and diluted	51,976,343	50,895,044
Weighted average common shares outstanding, basic and diluted	51,976,343	50,895,044
Comprehensive loss:
Net loss	$ (168,099)	$ (149,291)
Other comprehensive loss:
Unrealized losses on marketable securities	(302)	(242)
Comprehensive loss	$ (168,401)	$ (149,533)