Income Taxes (Tables)

12 Months Ended

Dec. 31, 2021

Income Tax Disclosure [Abstract]

Reconciliation of Federal Statutory Rate to Effective Tax Rate

The following table presents a reconciliation of the federal statutory rate of 21.0% to our effective tax rate for the periods presented:

	Year ended December 31,
	2021			2020
U.S. federal tax benefit at statutory rate		21.0	%		21.0	%
State income taxes, net of federal benefit		11.8	%		3.5	%
Non-deductible expenses and other		(0.3	)%		0.3	%
Stock-based compensation		(1.1	)%		(1.5	)%
Research and development credits		1.2	%		2.5	%
Transaction cost		3.9	%		—	%
Foreign rate differential		(3.1	)%		(4.3	)%
Change in valuation allowance, net		(33.4	)%		(21.5	)%
Effective tax rate		—	%		—	%

Schedule of Deferred Tax Assets

The Company did not have deferred tax liabilities as of December 31, 2021 and 2020. Significant components of the Company’s deferred tax assets are presented below:

	Year ended December 31,
	2021			2020
Deferred tax assets:
Net operating loss carryforwards	$	41,856		$	17,011
Research and development credit carryforward		4,545			2,810
Stock-based compensation		1,040			51
Property and equipment		178			40
Other accruals		734			464
Gross deferred tax assets		48,353			20,376
Valuation allowance		(48,353	)		(20,376	)
Total deferred tax assets—net	$	—		$	—

Reconciliation of Unrecognized Tax Benefits

Unrecognized Tax Benefits—The following is a tabular reconciliation of the total amounts of unrecognized tax benefits:

	Year ended December 31,
	2021		2020
Unrecognized tax benefits as of the beginning of the year	$	1,210	$	938
Increases (decreases) related to prior year tax provisions		40		(14	)
Increase related to current year tax provisions		431		286
Unrecognized tax benefits as of the end of the year	$	1,681	$	1,210