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Statement of Cash Flows (Statement) - USD ($)
3 Months Ended 6 Months Ended 12 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Dec. 31, 2020
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Cash Flows from Operating Activities:            
Net loss and comprehensive loss $ (190,993,000) $ (26,990,000)   $ (241,340,000) $ (29,704,000) $ (23,872,000)
Adjustments to reconcile net loss to net cash used in operating activities:            
Depreciation and amortization expense 4,902,000 2,398,000   11,734,000 6,407,000 5,433,000
Stock-based compensation expense 164,962,000 815,000   120,231,000 5,482,000 5,605,000
Provision for excess and obsolete inventory 1,821,000 0   0 0 0
Non-cash lease expense 191,000 1,052,000   2,400,000 (176,000) 437,000
Gain on extinguishment of debt       0 0 (4,500,000)
Loss from sale of lab equipment       0 0 105,000
Investment Income, Interest (21,000) (334,000)   (506,000) (988,000) 0
Change in operating assets and liabilities:            
Accounts receivable (1,446,000) (2,094,000)   (10,611,000) (4,567,000) (4,743,000)
Inventory (9,828,000) 2,675,000   (8,979,000) (7,970,000) (4,929,000)
Prepaid expenses and other current assets (6,466,000) (860,000)   2,498,000 (2,526,000) (1,534,000)
Due to/from related parties (688,000) (438,000)   (442,000) (919,000) (2,817,000)
Other assets 0 1,174,000   1,175,000 (4,395,000) (53,000)
Accounts payable and accrued expenses 3,458,000 1,725,000   14,805,000 12,847,000 2,311,000
Contract liabilities 1,027,000 (487,000)   (559,000) 2,342,000 0
Other current liabilities (9,148,000) (1,583,000)   15,960,000 4,451,000 3,873,000
Net cash used in operating activities (42,208,000) (22,613,000)   (93,128,000) (18,728,000) (24,684,000)
Investing activities            
Purchases of property and equipment (2,075,000) (3,907,000)   (24,094,000) (11,923,000) (2,183,000)
Proceeds from sale of equipment       0 0 125,000
Development of internal-use software assets (2,919,000) (1,414,000)   (7,880,000) (3,533,000) (1,745,000)
Net cash used in investing activities (4,994,000) (5,321,000)   (31,974,000) (15,456,000) (3,803,000)
Financing activities            
Capital contributions from ISMMS       0 30,897,000 24,636,000
Proceeds from long-term debt 0 6,000,000   15,928,000 0 4,500,000
Exercise of stock options 422,000 0   100,000 0 0
Long-term debt principal payments (394,000) 0   (186,000) 0 0
Capital lease principal payments (1,052,000) (1,343,000)   (4,010,000) (1,709,000) (2,071,000)
Payment of deferred transaction costs (1,254,000) 0        
Net cash provided by financing activities (2,278,000) 4,657,000   129,056,000 148,012,000 27,065,000
Net increase (decrease) in cash, cash equivalents and restricted cash (49,480,000) (23,277,000)   3,954,000 113,828,000 (1,422,000)
Cash, cash equivalents and restricted cash, at beginning of year 118,960,000 115,006,000   115,006,000 1,178,000 2,600,000
Cash, cash equivalents and restricted cash, at end of year 69,480,000 91,729,000 $ 118,960,000 118,960,000 115,006,000 1,178,000
Supplemental disclosures of cash flow information            
Interest expense paid 723,000 629,000   1,745,000 305,000 260,000
Purchases of property and equipment in accounts payable and accrued expenses 1,164,000 2,580,000   447,000 818,000 0
Software development costs in accounts payable and accrued expenses 1,570,000 1,023,000   1,473,000 1,040,000 334,000
Non-cash Series A redeemable convertible preferred stock dividends declared and paid       0 3,039,000 2,951,000
Forgiveness of principal on long-term debt       0 0 4,500,000
Assets acquired under capital leases obligations 615,000 4,340,000   7,546,000 9,796,000 5,670,000
Unpaid deferred transaction costs included in accounts payable and accrued expenses 4,228,000 $ 0        
Series B redeemable convertible preferred stock, $0.00001 par value: 338,663 shares authorized, issued and outstanding at December 31, 2020 and 2019; aggregate liquidation preference of $204,302 at December 31, 2020 and 2019            
Financing activities            
Proceeds from issuance of redeemable convertible preferred stock       0 118,824,000 0
Series C redeemable convertible preferred stock, $0.00001 par value: 197,824 shares authorized at December 31, 2020 and no shares authorized at December 31, 2019; 197,821 shares issued and outstanding at December 31, 2020 and no shares issued and outstanding at December 31, 2019; aggregate liquidation preference of $121,397 at December 31, 2020            
Financing activities            
Proceeds from issuance of redeemable convertible preferred stock       117,324,000 $ 0 $ 0
CM Life Sciences, Inc.            
Cash Flows from Operating Activities:            
Net loss and comprehensive loss (58,471,923)   (39,907,599)      
Adjustments to reconcile net loss to net cash used in operating activities:            
Change in fair value of warrants 56,637,684   38,510,584      
Investment Income, Interest (10,919)   (13,951)      
TransactionCosts     1,204,771      
Change in operating assets and liabilities:            
Prepaid expenses (16,723)   (277,031)      
Accrued expenses 1,394,615   97,120      
Net cash used in operating activities (467,266)   (386,106)      
Investing activities            
Investment of cash into Trust Account     (442,750,000)      
Net cash used in investing activities     (442,750,000)      
Financing activities            
Proceeds from sale of Units, net of underwriting discounts paid     433,895,000      
Proceeds from sale of Private Placement Warrants     10,855,000      
Proceeds from promissory note – related party     112,837      
Repayment of promissory note – related party     (165,081)      
Payment of offering costs     (466,969)      
Net cash provided by financing activities     444,230,787      
Net increase (decrease) in cash, cash equivalents and restricted cash (467,266)   1,094,681      
Cash, cash equivalents and restricted cash, at beginning of year 1,094,681          
Cash, cash equivalents and restricted cash, at end of year 627,415   1,094,681 $ 1,094,681    
Supplemental disclosures of cash flow information            
Initial classification of common stock subject to possible redemption     380,268,982      
Change in value of common stock subject to possible redemption $ (58,471,923)   (27,049,112)      
Initial classification of warrant liabilities     31,811,834      
Deferred underwriting fee payable     15,496,250      
Offering costs paid directly by Sponsor in consideration for the issuance of Class B common stock     25,000      
Payment of offering costs through promissory note — related party     $ 52,244