X0508 4 2023-07-21 0 0001818331 GeneDx Holdings Corp. WGS 0001307631 Meister Keith A. C/O CORVEX MANAGEMENT LP 667 MADISON AVENUE NEW YORK NY 10065 1 0 1 0 0 Stock Option (Right to Buy) 7.89 2023-07-21 4 A 0 8816 0.00 A 2033-07-20 Class A Common Stock 8816 8816 D Restricted Stock Unit 2023-07-21 4 A 0 5828 0.00 A Class A Common Stock 5828 5828 D The stock option shall vest the earlier of (a) the date of the next annual meeting of the Issuer's shareholders following the grant date, and (b) the first anniversary of the grant date, subject to the Reporting Person continuing to provide services to the Issuer through each vesting date. Each restricted stock unit ("RSU") represents a contingent right to receive 1 share of the Issuer's Class A Common Stock upon settlement for no consideration. The RSUs shall vest the earlier of (a) the date of the next annual meeting of the Issuer's shareholders following the grant date, and (b) the first anniversary of the grant date, subject to the Reporting Person continuing to provide services to the Issuer through each vesting date. /s/ Devin Schaffer, Attorney-in-Fact 2023-07-25