144 0002069239 XXXXXXXX LIVE 0001817713 JANUX THERAPEUTICS, INC. 001-40475 10955 VISTA SORRENTO PARKWAY SUITE 200 SAN DIEGO CA 92130 858-751-4493 Janeen Noel Doyle Officer Common Morgan Stanley Smith Barney LLC

1 New York Plaza 8th Floor New York NY 10004

4059 56943.71 60984354 06/02/2026 NASDAQ Common 06/01/2026 Restricted Stock Units vesting under registered plan Issuer N 4059 06/01/2026 Compensation for services rendered to Issuer Y This is a sell-to-cover transaction for taxes owed related to recent vesting of stock unit awards granted by the Issuer. 06/02/2026 /s/ Janeen Doyle