Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Income Statement [Abstract]
Collaboration revenue	$ 10,000	$ 10,588	$ 8,083
Operating expenses:
Research and development	125,896	68,388	54,922
General and administrative	41,771	41,047	26,140
Total operating expenses	167,667	109,435	81,062
Loss from operations	(157,667)	(98,847)	(72,979)
Other income:
Interest income	44,042	29,853	14,686
Total other income	44,042	29,853	14,686
Net loss	(113,625)	(68,994)	(58,293)
Other comprehensive gain (loss):
Unrealized gain on available-for-sale securities, net	2,153	1,498	2,200
Comprehensive loss	$ (111,472)	$ (67,496)	$ (56,093)
Net loss per common share, basic	$ (1.83)	$ (1.28)	$ (1.32)
Net loss per common share, diluted	$ (1.83)	$ (1.28)	$ (1.32)
Weighted-average shares of common stock outstanding, basic	61,966,999	53,751,480	44,016,283
Weighted-average shares of common stock outstanding diluted	61,966,999	53,751,480	44,016,283