Stockholders' Equity - Additional Information (Details) - USD ($)		1 Months Ended					12 Months Ended
	Jun. 10, 2021	Dec. 31, 2024	Mar. 31, 2024	Jul. 31, 2023	Jun. 30, 2021	Aug. 31, 2017	Dec. 31, 2025		Dec. 31, 2024	Dec. 31, 2023	May 31, 2024	May 31, 2023
Class Of Stock [Line Items]
Common stock, shares issued		59,064,606					60,384,283		59,064,606
Pre funded common stock warrants exercise price							$ 0.001
Common stock reserved for issuance		18,529,698					20,753,866		18,529,698	14,834,109
Weighted average grant date fair value per share of option grants							$ 38.1		$ 11.3	$ 10.02
Total Intrinsic value of stock options exercised							$ 6,700,000		$ 45,600,000	$ 1,900,000
Unrecognized stock-based compensation cost							$ 57,600,000
Unrecognized stock-based compensation cost, weighted-average period of recognition							2 years 3 months 18 days
Percentage of number of common stock shares	1.00%
Aggregate offering price of common stock		$ 59,000					$ 60,000		$ 59,000
Unvested shares		0					0		0	10,319
Unvested stock liabilities		$ 0					$ 0		$ 0	$ 20,000
BofA Securities, Inc [Member]
Class Of Stock [Line Items]
Aggregate offering price of common stock							150,000,000
Restricted Stock Unit ("RSU")
Class Of Stock [Line Items]
Unrecognized stock-based compensation cost							$ 25,700,000
Unrecognized stock-based compensation cost, weighted-average period of recognition							3 years
Transition and Consulting Agreement
Class Of Stock [Line Items]
Incremental stock-based compensation expense							$ 0		8,700,000
2021 Equity Incentive Plan
Class Of Stock [Line Items]
Incremental stock-based compensation expense							$ 0		$ 700,000
2017 Equity Incentive Plan | Employee Stock Option
Class Of Stock [Line Items]
Award vesting period						4 years
2021 Equity Incentive Plan
Class Of Stock [Line Items]
Percentage of annual increase in common stock available for issuance					5.00%
Shares authorized for issuance							13,571,381
2021 Equity Incentive Plan | Employee Stock Option
Class Of Stock [Line Items]
Award vesting period					4 years
2021 Equity Incentive Plan | Restricted Stock Unit ("RSU")
Class Of Stock [Line Items]
Number of shares outstanding		341,847					704,869	[1]	341,847	0
2021 Employee Stock Purchase Plan
Class Of Stock [Line Items]
Unrecognized stock-based compensation cost							$ 1,500,000
Unrecognized stock-based compensation cost, weighted-average period of recognition							1 year 7 months 6 days
Percentage of eligible earnings withheld to purchase shares of common stock	15.00%
Fair market value percentage price of common stock purchased	85.00%
Minimum increase in shares reserved for issuance									932,000
Stock-based compensation expense							$ 1,100,000		$ 800,000	$ 900,000
Maximum | BofA Securities, Inc [Member]
Class Of Stock [Line Items]
Aggregate offering price of common stock											$ 150,000,000	$ 150,000,000
Maximum | 2017 Equity Incentive Plan | Employee Stock Option
Class Of Stock [Line Items]
Award term						ten years
Maximum | 2021 Equity Incentive Plan | Employee Stock Option
Class Of Stock [Line Items]
Award term					ten years
Underwritten Offering
Class Of Stock [Line Items]
Common stock, shares issued		6,150,793	5,397,301	4,153,717					6,150,793
Price of common stock sold per share		$ 63	$ 46.5	$ 12.46					$ 63
Pre funded common stock warrants exercise price		$ 0.001	$ 0.001	$ 0.001
Underwritten Offering | Pre-funded Warrants
Class Of Stock [Line Items]
Warrants to purchase shares of common stock		238,095	1,935,483	583,483					238,095
Price of warrants sold per share		$ 62.999	$ 46.499	$ 12.459					$ 62.999
Gross proceeds from issuance of common stock		$ 402,500,000	$ 341,000,000	$ 59,000,000
Aggregate fees amount related to offering included in underwriting discounts commissions and offering expenses		24,600,000	20,900,000	2,500,000
Net proceeds after deducting underwriting discounts and commissions, and offering expenses		$ 377,900,000	$ 320,100,000	$ 56,500,000

[1] This amount includes 18,296 vested and unsettled RSUs granted to the Company’s non-employee directors who have elected deferred settlement of the RSUs to a specified date following the first to occur of (i) the date that is 30 days following the date of the director's separation from service for any reason, or (ii) a change in control event.