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Research Collaboration and Exclusive License Agreement - Additional Information (Detail)
$ in Millions
1 Months Ended 12 Months Ended
Jun. 30, 2024
USD ($)
Dec. 31, 2024
USD ($)
Target
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Merck Agreement First Collaboration Target        
Research And Development Arrangement Contract To Perform For Others [Line Items]        
Non-refundable and non-creditable upfront fee   $ 8.0    
Initial Transaction Price   11.4    
Developmental milestone $ 7.5      
Reimbursable research program funding for collaboration target   3.4    
Merck Agreement Second Collaboration Target        
Research And Development Arrangement Contract To Perform For Others [Line Items]        
Non-refundable and non-creditable upfront fee   8.0    
Initial Transaction Price   12.0    
Reimbursable research program funding for collaboration target   $ 4.0    
Merck Agreement        
Research And Development Arrangement Contract To Perform For Others [Line Items]        
Number of collaboration targets | Target   2    
Non-refundable and non-creditable upfront fee   $ 8.0    
Payable upon selection of second collaboration target   8.0    
Milestone payments   285.0    
Revenue recognized   10.6 $ 8.1 $ 8.6
Merck Agreement | Maximum        
Research And Development Arrangement Contract To Perform For Others [Line Items]        
Milestone payments per collaboration target   142.5    
Milestone payments upon successful completion of certain commercial milestones   $ 350.0