Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022
Cash flows from operating activities
Net loss	$ (58,293)	$ (63,059)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	1,955	841
Stock-based compensation	20,005	17,203
Accretion of discounts on investments, net	(7,688)	(2,183)
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	210	(3,369)
Other long-term assets	(1,119)	(1,270)
Accounts payable	277	(294)
Accrued expenses	(678)	4,156
Deferred revenue	(5,922)	1,764
Operating lease right-of-use assets and liabilities, net	678	3,289
Net cash used in operating activities	(50,575)	(42,922)
Cash flows from investing activities
Purchases of property and equipment	(1,850)	(6,445)
Purchases of short-term investments	(317,344)	(294,389)
Maturities of short-term investments	278,000	359,100
Net cash provided by (used in) investing activities	(41,194)	58,266
Cash flows from financing activities
Proceeds from exercise of common stock options and employee stock purchase plan	3,018	500
Proceeds from the issuance of common stock and pre-funded common stock warrants, net of issuance costs	56,530	0
Net cash provided by financing activities	59,548	500
Net increase (decrease) in cash, cash equivalents and restricted cash	(32,221)	15,844
Cash, cash equivalents and restricted cash - beginning of year	52,242	36,398
Cash, cash equivalents and restricted cash - end of period	20,021	52,242
Supplemental disclosure of noncash investing and financing activities
Unpaid property and equipment	132	109
Vesting of restricted common stock	149	1,034
Unrealized gain (loss) on available-for-sale securities, net	2,200	(1,265)
Operating lease liabilities arising from right-of-use assets	$ 0	$ 23,422