Convertible Preferred Stock and Stockholders’ Equity (Deficit) (Tables)

3 Months Ended

Mar. 31, 2022

Equity [Abstract]

Summary of Stock Option Activity

	Number of Outstanding Options			Weighted- Average Exercise Price		Weighted- Average Remaining Contractual Term (in years)		Aggregate Intrinsic Value
Balance at December 31, 2021		5,654,663		$	9.65		9.22	$	62,954
Granted		1,611,590		$	19.54
Exercised		(6,405	)	$	0.11
Forfeited or cancelled		(137,628	)	$	13.46
Balance at March 31, 2022		7,122,220		$	11.82		9.16	$	35,024
Vested and expected to vest at March 31, 2022		7,122,220		$	11.82		9.16	$	35,024
Exercisable at March 31, 2022		4,982,978		$	7.35		8.93	$	35,024

Summary of Fair Value of Stock Option Grants

The assumptions used in the Black-Scholes option pricing model to determine the fair value of stock option grants under its Plans were as follows:

	Three Months Ended March 31,
	2022		2021
Risk-free interest rate	1.5% – 1.7%		0.9% – 1.6%
Expected volatility	84% – 85%		86%
Expected term (in years)	6.1		5.5 – 10.0
Expected dividend yield		—		—

Summary of Stock-Based Compensation Expense

	Three Months Ended  March 31,
	2022		2021
Research and development	$	1,660	$	32
General and administrative		2,298		91
Total	$	3,958	$	123

Summary of Unvested Shares and Unvested Stock Liabilities

A summary of the Company’s unvested shares and unvested stock liabilities is as follows (in thousands, except share data):

	Number of Unvested Shares			Unvested Stock Liabilities
Balance at December 31, 2021		379,825		$	1,203
Early exercised shares		—			—
Vested shares		(144,118	)		(503	)
Balance at March 31, 2022		235,707		$	700

Summary of Common Stock Reserved for Future Issuance

	March 31,		December 31,
	2022		2021
Common stock options outstanding		7,122,220		5,654,663
Shares available for issuance under the Plans		4,236,225		3,629,039
Shares available for issuance under the ESPP		870,777		454,548
Total		12,229,222		9,738,250