David Pezeshki, as attorney-in-fact for Corey Goodman and Robert Adelman, Directors of the General Partner of the General Partner

SCHEDULE 13G/A 0001739920 XXXXXXXX LIVE 2 Common Stock, $0.0001 par value per share 03/31/2025 0001817241 Artiva Biotherapeutics, Inc. 04317A107 5505 Morehouse Drive Suite 100 San Diego CA 92121 Rule 13d-1(c) venBio Global Strategic Fund III, L.P. E9 0 1198975 0 1198975 1198975 N 4.9 PN VENBIO GLOBAL STRATEGIC GP III, L.P. E9 0 1198975 0 1198975 1198975 N 4.9 HC PN VENBIO GLOBAL STRATEGIC GP III, LTD E9 0 1198975 0 1198975 1198975 N 4.9 CO HC Adelman Robert J X1 0 1198975 0 1198975 1198975 N 4.9 IN HC GOODMAN COREY S X1 0 1198975 0 1198975 1198975 N 4.9 IN HC Artiva Biotherapeutics, Inc. 5505 Morehouse Drive, Suite 100, San Diego, California, 92121 This Statement is filed on behalf of the following persons (collectively, the "Reporting Persons"): i. venBio Global Strategic Fund III, L.P. ("Fund III"); ii. venBio Global Strategic GP III, L.P. ("General Partner III"); iii. venBio Global Strategic GP III, Ltd. ("GP Ltd. III"); iv. Robert Adelman ("Mr. Adelman"); and v. Corey Goodman ("Mr. Goodman"). This Statement relates to shares of Common Stock ("Shares") directly beneficially owned by Fund III. General Partner III is the sole general partner of Fund III, and GP Ltd. III is the sole general partner of General Partner III. Mr. Adelman and Mr. Goodman are directors of GP Ltd. III (collectively, the "Directors"). Accordingly, each of General Partner III, GP Ltd. III, and the Directors may be deemed to indirectly beneficially own the Shares reported herein. Dr. Aaron Royston is also a director of GP Ltd. III but disclaims beneficial ownership over the securities held by Fund III. The address of the principal business office of each Reporting Person is c/o venBio Partners, LLC, 1700 Owens Street, Suite 595, San Francisco, CA 94158. Each of Fund III and General Partner III is a Cayman Islands exempted limited partnership. GP Ltd. III is a Cayman Islands exempted company. Each of the Directors is a citizen of the United States of America. Y As of March 31, 2025, each of the Reporting Persons may be deemed to beneficially own 1,198,975 Shares. Each Reporting Person disclaims beneficial ownership of such securities except for the Shares, if any, such Reporting Person holds of record. The percentages set forth in Line 11 of the cover sheets are based on 24,363,119 Shares outstanding as of March 31, 2025, as reported in the Issuer's definitive proxy statement on Schedule 14A filed with the Securities and Exchange Commission on April 29, 2025. See Line 5 of cover sheets. See Line 6 of cover sheets. See Line 7 of cover sheets. See Line 8 of cover sheets. N Y Y N See disclosure in Item 2 hereof. Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Exhibit 1: Joint Filing Agreement Exhibit 2: Power of Attorney regarding filings under the Securities Exchange Act of 1934, as amended. venBio Global Strategic Fund III, L.P. /s/ David Pezeshki David Pezeshki, as attorney-in-fact for Corey Goodman and Robert Adelman, Directors of the General Partner of the General Partner 05/15/2025 VENBIO GLOBAL STRATEGIC GP III, L.P. /s/ David Pezeshki David Pezeshki, as attorney-in-fact for Corey Goodman and Robert Adelman, Directors of the General Partner 05/15/2025 VENBIO GLOBAL STRATEGIC GP III, LTD /s/ David Pezeshki David Pezeshki, as attorney-in-fact for Corey Goodman and Robert Adelman, Directors 05/15/2025 Adelman Robert J /s/ David Pezeshki David Pezeshki, as attorney-in-fact 05/15/2025 GOODMAN COREY S /s/ David Pezeshki David Pezeshki, as attorney-in-fact 05/15/2025 This Schedule 13G was executed by David Pezeshki on behalf of the individuals listed above pursuant to a Power of Attorney, a copy of which is attached as Exhibit 2.