X0306 4 2022-09-01 0 0001817229 Vor Biopharma Inc. VOR 0001840685 Chakraborty Tirtha C/O VOR BIOPHARMA INC. 100 CAMBRIDGEPARK DRIVE, SUITE 101 CAMBRIDGE MA 02140 0 1 0 0 Chief Scientific Officer Common Stock 2022-09-01 4 A 0 76000 0.00 A 96980 D Employee Stock Option (right to buy) 5.31 2022-09-01 4 A 0 76000 0.00 A 2032-08-31 Common Stock 76000 76000 D Represents the number of shares underlying restricted stock units ("RSUs"). Each RSU represents the contingent right to receive one share of common stock of the Issuer. The RSUs vest in four equal installments on each of March 1, 2023, September 1, 2023, March 1, 2024 and September 1, 2024, in each case, subject to the Reporting Person's continued service as of each such date. The shares shall vest and become exercisable in a series of 24 successive equal monthly installments beginning on October 1, 2022, in each case subject to the Reporting Person's continued service as of each such date. /s/ Rich Segal, Attorney-in-Fact 2022-09-06