X0206 3 2021-02-04 0 0001817229 Vor Biopharma Inc. VOR 0001841150 Slapak Christopher C/O VOR BIOPHARMA INC. 100 CAMBRIDGEPARK DRIVE, SUITE 400 CAMBRIDGE MA 02140 0 1 0 0 Chief Medical Officer Employee Stock Option (right to buy) 1.90 2030-08-24 Common Stock 153119 D Employee Stock Option (right to buy) 1.90 2030-08-20 Common Stock 153088 D 1/4th of the shares underlying the option vest on July 30, 2020, with the remainder vesting in equal monthly installments over 3 years, provided that the Reporting Person remains continuously engaged by the Issuer on each such vesting date. 1/48th of the shares underlying the option vest or vested in equal monthly installments commencing on September 1, 2020, provided that the Reporting Person remains continuously engaged by the Issuer on each such vesting date. /s/ Jason Minio, Attorney-in-Fact 2021-02-04