CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023
Cash flows from operating activities
Net loss	$ (86,202)	$ (91,602)
Adjustments to reconcile net loss to net cash used in operations:
Depreciation expense	2,663	2,600
Non-cash lease expense	3,752	3,513
Stock-based compensation	8,138	11,468
Interest amortization on marketable securities	(1,137)	(3,674)
Changes in operating assets and liabilities:
Operating lease liabilities	(2,806)	(2,646)
Prepaid expenses and other current assets	(859)	2,558
Accounts payable and accrued liabilities	(1,446)	2,678
Other assets	2,300	(1,161)
Net cash used in operating activities	(75,597)	(76,266)
Cash flow from investing activities
Purchases of marketable securities	(9,914)	(58,369)
Proceeds from maturities of marketable securities	107,000	120,000
Purchases of property and equipment	(157)	(958)
Net cash provided by investing activities	96,929	60,673
Cash flow from financing activities
Payment of issuance costs related to underwritten public offering and concurrent private placement		(717)
Proceeds from the issuance of common stock from at-the-market sales agreement, net of issuance costs	297	4,593
Repurchases of shares for tax withholdings upon vesting of restricted stock unit awards	(303)	(1,165)
Proceeds from stock option exercises and the issuance of shares under ESPP	112	202
Net cash provided by financing activities	106	2,913
Net decrease in cash, cash equivalents and restricted cash equivalents	21,438	(12,680)
Cash, cash equivalents and restricted cash equivalents, beginning of period	33,773	60,119
Cash, cash equivalents and restricted cash equivalents, end of period	55,211	47,439
Supplemental disclosure of non-cash activities
Right-of-use assets obtained in exchange for lease obligations		37
Purchases of property and equipment in accounts payable and accrued liabilities		63
Financing costs associated with the sale of common stock included in accounts payable and accrued expenses	$ 22	$ 30