X0306 4 2021-02-11 0 0001549595 Nurix Therapeutics, Inc. NRIX 0001817217 van Houte Hans C/O NURIX THERAPEUTICS, INC. 1700 OWENS STREET, SUITE 205 SAN FRANCISCO CA 94158 0 1 0 0 Chief Financial Officer Employee Stock Option (right to buy) 38.97 2021-02-11 4 A 0 40000 0.00 A 2031-02-10 Common Stock 40000 40000 D The stock option vests as to 1/48 of the total shares monthly beginning March 11, 2021 until the option is fully vested on February 11, 2025, subject to the Reporting Person's provision of service to the Issuer on each vesting date. /s/ Christine Ring, as Attorney-in-Fact for Hans van Houte 2021-02-12