X0306 4 2022-01-19 0 0001549595 Nurix Therapeutics, Inc. NRIX 0001817199 Ring Christine C/O NURIX THERAPEUTICS, INC. 1700 OWENS STREET, SUITE 205 SAN FRANCISCO CA 94158 0 1 0 0 General Counsel Employee Stock Option (right to buy) 19.49 2022-01-19 4 A 0 69262 0.00 A 2032-01-18 Common Stock 69262 69262 D Restricted Stock Units 0.00 2022-01-19 4 A 0 30785 0.00 A Common Stock 30785 30785 D The stock option vests as to 1/48 of the total shares monthly beginning February 19, 2022 until the option is fully vested on January 19, 2026, subject to the Reporting Person's provision of service to the Issuer on each vesting date. Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock. The RSUs will vest in substantially equal increments quarterly over four years, with the first quarterly increment vesting on April 30, 2022, subject to the Reporting Person's provision of services to the Issuer on each vesting date. Shares of the Issuer's Common Stock will be delivered to the Reporting Person following vesting. RSUs do not expire; they either vest or are canceled prior to the vest date. /s/ Christine Ring 2022-01-21