X0306 4 2021-02-08 0 0001807901 Pandion Therapeutics, Inc. PAND 0001816744 Viney Joanne L. C/O PANDION THERAPEUTICS, INC., 134 COOLIDGE AVENUE WATERTOWN MA 02472 0 1 0 0 See Remarks Stock Option (right to buy) 17.75 2021-02-08 4 A 0 73789 0.00 A 2031-02-07 Common Stock 73789 73789 D This option award was granted on February 8, 2021. 1/4 of the shares underlying the award shall vest on February 8, 2022, with the remainder of the shares vesting in equal monthly installments following February 8, 2022 through February 8, 2025, subject to the reporting person's continued service on each applicable vesting date. President and Chief Scientific Officer /s/ Edward D. Freedman, as attorney-in-fact for Joanne Viney 2021-02-10