X0206 3 2022-12-29 0 0001816736 Disc Medicine, Inc. IRON 0001952556 MacDonald Brian Richard C/O DISC MEDICINE, INC. 321 ARSENAL STREET, SUITE 101 WATERTOWN MA 02472 0 1 0 0 Chief Innovation Officer Common Stock 27400 D Common Stock 1096 I Held by Son Common Stock 1096 I Held by Son Common Stock 1096 I Held by Son Stock Option (Right to Buy) 1.01 2030-03-10 Common Stock 37214 D Stock Option (Right to Buy) 9.86 2031-09-13 Common Stock 50491 D The Reporting Person disclaims any beneficial ownership of the reported shares other than to the extent of any pecuniary interest he may have therein, directly or indirectly. 8,503 shares underlying this option vested immediately upon grant, with the remaining shares vesting in 15 equal quarterly installments following September 13, 2019, subject to the Reporting Person's continued service on each such vesting date The shares underlying this option vest in 48 equal monthly installments following September 1, 2021, subject to the Reporting Person's continued service on each such vesting date. Exhibit 24 - Power of Attorney /s/ Rahul Khara, attorney-in-fact 2023-01-03