Segment Reporting (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2024 USD ($) segment	Dec. 31, 2023 USD ($)
Segment Reporting [Abstract]
Number of operating segments | segment	1
Revenue, Major Customer [Line Items]
Research and development	$ 119,039	$ 87,518
General and administrative	59,166	49,401
Total operating expenses	178,205	136,919
Operating loss	(178,205)	(136,919)
Benefit from R&D tax credit	21,097	12,875
Interest income	8,268	4,623
Interest expense	4,479	2,204
Foreign exchange (losses) gains	(1,032)	3,686
Other income	823	255
Income tax expense	1,594	780
Net loss	(155,122)	(118,464)
Single Operating Segment
Revenue, Major Customer [Line Items]
Total operating expenses	178,205	136,919
Operating loss	(178,205)	(136,919)
Benefit from R&D tax credit	21,097	12,875
Interest income	8,268	4,623
Interest expense	(4,479)	(2,204)
Foreign exchange (losses) gains	(1,032)	3,686
Other income	823	255
Income tax expense	(1,594)	(780)
Net loss	(155,122)	(118,464)
Development expenses | Single Operating Segment
Revenue, Major Customer [Line Items]
Research and development	76,993	48,306
Personnel expenses | Single Operating Segment
Revenue, Major Customer [Line Items]
Research and development	26,707	23,533
General and administrative	23,422	18,192
Legal and professional fees | Single Operating Segment
Revenue, Major Customer [Line Items]
General and administrative	14,535	9,800
Non-cash share-based compensation expense | Single Operating Segment
Revenue, Major Customer [Line Items]
Research and development	10,309	8,910
General and administrative	9,208	8,367
Facilities and other expenses | Single Operating Segment
Revenue, Major Customer [Line Items]
Research and development	5,030	6,769
General and administrative	$ 12,001	$ 13,042