Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss	$ (91,505)	$ (71,742)	$ (60,334)
Adjustments to reconcile net loss to net cash used in operating activities
Depreciation and amortization	330	175	112
Change in fair value of convertible notes	0	0	1,771
Non-cash loss on foreign currency remeasurement	1,141	22	0
Non-cash share-based compensation	13,123	8,639	17,983
Non-cash lease expenses	2,126	1,797	0
Changes in operating assets and liabilities
Prepaid expenses and other current assets	(28,760)	(8,984)	(4,490)
Deferred and prepaid tax assets	(1,701)	(877)	(221)
Other assets	(307)	(160)	(57)
Operating lease liabilities	(2,081)	(1,880)	0
Accounts payable	2,497	(163)	1,303
Accrued expenses and other liabilities	(314)	5,428	2,553
Net cash used in operating activities	(105,451)	(67,745)	(41,380)
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchases of property and equipment	(596)	(334)	(131)
Purchase of investments	0	0	(497)
Net cash used in investing activities	(596)	(334)	(628)
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from issuance of ordinary shares, net of issuance costs	440	154,794	0
Proceeds from the issuance of shares under the employee share purchase plan	199	0	0
Proceeds from exercise of share options	401	1,852	16
Issuance of ADRs in initial public offering, net of issuance costs	0	0	132,823
Proceeds of issuance of preferred shares, net of issuance costs	0	0	61,316
Net cash provided by financing activities	1,040	156,646	194,155
Effect of exchange rate changes on cash, cash equivalents and restricted cash	(24,959)	(5,576)	13,225
Net (decrease)/increase in cash, cash equivalents and restricted cash	(129,966)	82,991	165,372
Cash, cash equivalents and restricted cash, beginning of the period	273,347	190,356	24,984
Cash, cash equivalents and restricted cash, end of the period	143,381	273,347	190,356
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:
Right-of-use assets obtained in exchange for new operating lease liabilities	783	5,562	0
Unpaid tax withholdings on stock award recognized in accrued and other liabilities	85	0	0
Proceeds from exercise of options were received and recorded in other current assets	0	53	0
Deferred issuance costs included in accrued expenses	0	856	0
Conversion of convertible notes into convertible preferred shares	0	0	21,614
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Abstract]
Cash and cash equivalents	143,206	273,243	190,327
Short-term restricted cash	175	104	29
Total cash, cash equivalents and restricted cash	$ 143,381	$ 273,347	$ 190,356