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Summary of Significant Accounting Policies - Narrative (Details)
£ in Thousands, € in Millions
12 Months Ended
Aug. 28, 2019
GBP (£)
Dec. 31, 2022
USD ($)
region
Dec. 31, 2022
GBP (£)
region
Dec. 31, 2022
EUR (€)
region
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Jan. 01, 2021
USD ($)
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Consideration received on transaction | £ £ 25,000            
Number of geographic regions | region   2 2 2      
Expected dividend yield (in percent)   0.00% 0.00% 0.00% 0.00% 0.00%  
Operating lease right-of-use assets   $ 2,006,000     $ 3,696,000   $ 1,000,000
Operating lease liabilities - current   1,510,000     2,235,000   $ 1,000,000
Foreign exchange gains   821,000     1,990,000 $ (11,702,000)  
Accrued interest and penalties related to unrecognized tax benefits   $ 0     $ 0 $ 0  
Maximum qualifying research and development expenditures with connected parties, percent   15.00% 15.00% 15.00%      
United Kingdom Research and Development Tax Credit Regime, Small or Medium-Sized Enterprises (SME)              
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Cash rebate percent (in percent)   33.35% 33.35% 33.35%      
Total aid claimable (in Euros) | €       € 7.5      
Cap on payable claims (in GBP) | £     £ 20        
United Kingdom Research and Development Tax Credit Regime              
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Cash rebate percent (in percent)   21.67% 21.67% 21.67%      
Annual offset amount (in GBP) | £     £ 5,000        
Percentage of taxable profits (in percent)   50.00% 50.00% 50.00%