Nature of Business (Details) £ / shares in Units, $ / shares in Units, $ in Thousands, £ in Millions					1 Months Ended		12 Months Ended
	Dec. 14, 2022 $ / shares shares	Oct. 08, 2021 USD ($)	Sep. 22, 2020 USD ($) shares	Aug. 28, 2019 GBP (£)	May 31, 2021 USD ($)	May 19, 2021 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	Sep. 22, 2020 £ / shares
Conversion of Stock [Line Items]
Consideration received on transaction | £				£ 25.0
Ordinary share conversion ratio		1
Net loss							$ 91,505	$ 71,742	$ 60,334
Accumulated deficit							261,146	169,641
Cash and cash equivalents							143,206	$ 273,243	$ 190,327
Initial Public Offering
Conversion of Stock [Line Items]
Consideration received on transaction			$ 132,800		$ 154,800	$ 154,800
Accumulated deficit							$ 261,100
Initial Public Offering | American Depositary Shares
Conversion of Stock [Line Items]
Maximum amount of stock that may be sold		$ 150,000
Sale of stock, shares issued in transaction (in shares) | shares			8,625,000
Sale of stock, price per share (in dollars per share) | £ / shares										£ 17.00
At-The-Market Offering
Conversion of Stock [Line Items]
Sale of stock, shares issued in transaction (in shares) | shares	44,416
Sale of stock, price per share (in dollars per share) | $ / shares	$ 10.53