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Ordinary Shares (Details)
3 Months Ended
Mar. 31, 2022
vote
shares
Mar. 31, 2021
shares
Class of Stock [Line Items]    
Exercise of share options (in shares) 376,158  
Restricted share units for which no shares were issued (in shares) 57,875  
Ordinary shares    
Class of Stock [Line Items]    
Number of votes | vote 1  
Ordinary shares | Common stock    
Class of Stock [Line Items]    
Exercise of share options (in shares) 376,158 581,328
Exercise of share options, including prior period exercises issued in period (in shares)   813,555
Issuance of shares (in shares)   232,227
Vesting of restricted stock units (in shares) 68,534  
Restricted stock award, issued and vested in period (shares) 10,659