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Net Loss Per Share
3 Months Ended
Mar. 31, 2022
Earnings Per Share [Abstract]  
Net Loss Per Share Net Loss Per Share
Basic and diluted net loss per share attributable to ordinary shareholders was calculated as follows (in thousands, except share and per share amounts):
Three Months Ended March 31,
20222021
Numerator
Net loss$(21,171)$(12,715)
Net loss attributable to ordinary shareholders - basic and diluted$(21,171)$(12,715)
Denominator
Weighted-average number of ordinary shares used in net loss per share - basic and diluted42,036,563 36,569,290 
Net loss per share - basic and diluted$(0.50)$(0.35)
The Company’s potentially dilutive securities, which include unvested ordinary shares, unvested restricted share units, and options granted, have been excluded from the computation of diluted net loss per share as the effect would be to reduce the net loss per share. Therefore, the weighted-average number of ordinary shares outstanding used to calculate both basic and diluted net loss per share attributable to ordinary shareholders is the same. The Company excluded the following potential ordinary shares, presented based on amounts outstanding at each period end, from the computation of diluted net loss per share attributable to ordinary shareholders for the three months ended March 31, 2022, and 2021 because including them would have had an anti-dilutive effect:
Three Months Ended March 31,
20222021
Unvested ordinary shares— 5,503 
Unvested restricted share units197,071 217,482 
Share options4,559,112 4,026,508 
4,756,183 4,249,493