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Share-Based Compensation - Narrative (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended 24 Months Ended
May 19, 2020
shares
Aug. 17, 2018
Aug. 17, 2017
May 31, 2021
shares
Jun. 30, 2021
USD ($)
shares
Jun. 30, 2020
USD ($)
Jun. 30, 2021
USD ($)
day
$ / shares
shares
Jun. 30, 2021
USD ($)
£ / shares
shares
Jun. 30, 2020
USD ($)
period
shares
Jun. 30, 2020
£ / shares
Dec. 31, 2020
Aug. 17, 2020
Sep. 30, 2020
shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Share-based compensation expense         $ 1,904 $ 9,698 $ 3,570   $ 11,402        
Number of periods | period                 11        
Granted (in dollars per share) | £ / shares               £ 25.29   £ 8.19      
Unrecognized compensation cost of options         21,500   21,500 £ 21,500          
Weighted average grant date fair value of shares granted (in dollars per share) | £ / shares               £ 25.29   8.19      
Research and Development Expense                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Share-based compensation expense         934 2,587 1,735   $ 3,517        
General and Administrative Expense                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Share-based compensation expense         970 $ 7,111 $ 1,835   7,885        
United Kingdom Employee                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Period for recognition             3 years 2 months 12 days            
Weighted average exercise price (in dollars per share) | £ / shares                   0.36      
United States Employee                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Weighted average exercise price (in dollars per share) | £ / shares                   £ 2.35      
Share-based Payment Arrangement, Tranche One | Ordinary Shares                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Award vesting percentage     25.00%                    
Share-based Payment Arrangement, Tranche Two | Ordinary Shares                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Award vesting percentage   25.00%                      
Share-based Payment Arrangement, Tranche Three | Ordinary Shares                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Award vesting percentage                       50.00%  
Ordinary Shares                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Granted (in shares) | shares             0            
Granted (in dollars per share) | $ / shares             $ 0            
Weighted average grant date fair value of shares granted (in dollars per share) | $ / shares             $ 0            
Share options | Research and Development Expense                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Share-based compensation expense                 2,200        
Share options | General and Administrative Expense                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Share-based compensation expense                 $ 6,700        
Share options | Ordinary Shares                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Granted (in shares) | shares             312,132   2,463,136        
Restricted Share Units (RSUs)                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Vested (in shares) | shares       19,583     19,583            
Vested in period, fair value             $ 100   $ 900        
Unrecognized compensation cost         $ 1,800   $ 1,800 £ 1,800          
Period for recognition             3 years 18 days            
Exercise price (in pound sterling per share) | £ / shares               £ 0.01          
2017 Equity Incentive Plan | President and Chief Business Officer                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Granted (in shares) | shares 1,015,813               973,487        
2017 Equity Incentive Plan | Ordinary Shares                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Number of shares authorized | shares         13,601,246   13,601,246 13,601,246          
Number of shares available for issuance | shares         440,207   440,207 440,207          
2017 Equity Incentive Plan | Share options                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Award vesting period                 3 years        
Share-based compensation expense                 $ 8,900        
Expiration period             10 years            
2017 Equity Incentive Plan | Share options | Share-based Payment Arrangement, Tranche One                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Award vesting percentage                     33.30%    
2017 Equity Incentive Plan | Share options | Share-based Payment Arrangement, Tranche Two                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Award vesting percentage                     25.00%    
2017 Equity Incentive Plan | Share options | Share-based Payment Arrangement, Tranche Three                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Award vesting percentage                     75.00%    
2017 Equity Incentive Plan | Share options | Minimum                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Award vesting period                     3 years    
2017 Equity Incentive Plan | Share options | Maximum                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Award vesting period                     4 years    
2017 Equity Incentive Plan | Restricted Share Units (RSUs)                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Award vesting period                     4 years    
Award vesting percentage                     25.00%    
2017 Equity Incentive Plan | Restricted Share Units (RSUs) | Share-based Payment Arrangement, Tranche One                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Award vesting percentage             25.00%            
Percentage amount closing price is higher than listing price             20.00%            
Threshold consecutive trading days | day             5            
2017 Equity Incentive Plan | Restricted Share Units (RSUs) | Share-Based Payment Arrangement, Tranche Four                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Award vesting percentage             6.25%            
2020 Share Option Plan | Ordinary Shares                          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                          
Shares reserved for future issuance | shares         2,074,325   2,074,325 2,074,325         2,074,325
Maximum percentage of shares outstanding number of shares reserved for issuance may increase                         4.00%
Number of shares available for grant | shares         931,309   931,309 931,309