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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2020
Income Tax Disclosure [Abstract]  
Schedule of Components of Income Tax Expense (Benefit) The income tax provision for the years then ended comprised (in thousands):
Year Ended December 31,
20202019
Current income tax provision
United Kingdom$— $— 
Foreign253 15 
Total current expense:$253 $15 
Deferred income tax benefit:
United Kingdom— — 
Foreign(221)— 
Total deferred income tax benefit:(221)— 
Total provision for income taxes$32 $15 
Schedule of Effective Income Tax Rate Reconciliation
A reconciliation of income tax expense computed at the statutory UK income tax rate to income taxes as reflected in the consolidated financial statements is as follows (in thousands):
Year Ended December 31,
20202019
Income taxes at UK statutory rate$(11,458)$(3,724)
Permanent differences340 238 
UK R&D tax credit1,664 1,036 
Change in valuation allowance8,683 2,205 
State income taxes(5)
Deferred tax asset true-up919 — 
Other(111)255 
$32 $15 
Schedule of Deferred Tax Assets and Liabilities
Significant components of the Company’s deferred tax assets and liabilities as of December 31, 2020 and 2019 consist of the following (in thousands):
Year Ended December 31,,
20202019
Net operating loss carryforward$10,075 $2,936 
Charitable contributions— 
Share-based compensation3,128 757 
Reserves and accruals62 — 
Total deferred tax assets13,265 3,695 
Valuation allowance$(13,000)$(3,665)
Depreciation(44)(30)
Total deferred tax liabilities(44)(30)
Net deferred tax assets$221 $— 
Summary of Valuation Allowance
Changes in the valuation allowance for deferred tax assets during the years ended December 31, 2020 and 2019 related primarily to the increases in net operating loss and were as follows (in thousands):
Year Ended December 31,
20202019
Valuation allowance at beginning of year$3,665 $1,321 
Increases recorded to income tax provision8,683 2,344 
Increases recorded to CTA652 
Decreases recorded to income tax provision— — 
Valuation allowance at end of year$13,000 $3,665