The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AARDVARK THERAPEUTICS INC COM 002942100   4,078,861 306,912 SH   SOLE   373,594 0 0
ABEONA THERAPEUTICS INC COM NEW 00289Y206   5,252,301 994,754 SH   SOLE   994,754 0 0
ABIVAX SA SPONSORED ADS 00370M103   45,820,870 539,704 SH   SOLE   539,704 0 0
AKERO THERAPEUTICS INC COM 00973Y108   30,559,837 643,636 SH   SOLE   643,636 0 0
ALKERMES PLC SHS G01767105   5,415,390 180,513 SH   SOLE   180,513 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   9,513,000 700,000 SH   SOLE   700,000 0 0
ARCTURUS THERAPEUTICS HLDGS COM 03969T109   63,491 3,445 SH   SOLE   3,445 0 0
ARCTURUS THERAPEUTICS HLDGS PUT 03969T959   774,060 42,000 SH Put SOLE   42,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   10,647,071 53,554 SH   SOLE   53,554 0 0
ATYR PHARMA INC PUT 002120952   901,250 1,250,000 SH Put SOLE   1,250,000 0 0
AVALO THERAPEUTICS INC COM NEW 05338F306   9,162,919 720,922 SH   SOLE   720,922 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   36,800,660 844,633 SH   SOLE   844,633 0 0
BENITEC BIOPHARMA INC COM NEW 08205P209   3,876,026 276,267 SH   SOLE   276,267 0 0
BICARA THERAPEUTICS INC COM 055477103   3,957,069 250,606 SH   SOLE   250,606 0 0
BIODESIX INC COM 09075X207   374,533 49,607 SH   SOLE   49,607 0 0
BIOGEN INC COM 09062X103   11,265,094 80,419 SH   SOLE   80,419 0 0
BRIDGEBIO ONCOLOGY THERAPEUT COM NEW 107924102   5,296,854 457,414 SH   SOLE   457,414 0 0
C4 THERAPEUTICS INC COM STK 12529R107   4,212,190 1,897,383 SH   SOLE   1,897,383 0 0
CAMP4 THERAPEUTICS CORP COM 13463J101   1,960,782 653,594 SH   SOLE   653,594 0 0
CAPRICOR THERAPEUTICS INC PUT 14070B959   1,043,287 144,700 SH Put SOLE   144,700 0 0
CELCUITY INC COM 15102K100   4,381,088 88,686 SH   SOLE   88,686 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   9,026,612 348,922 SH   SOLE   348,922 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   3,425,022 141,238 SH   SOLE   141,238 0 0
CERUS CORP COM 157085101   4,318,100 2,715,786 SH   SOLE   2,715,786 0 0
CG ONCOLOGY INC COM 156944100   25,712,577 638,346 SH   SOLE   638,346 0 0
CIDARA THERAPEUTICS INC COM NEW 171757206   21,153,576 220,902 SH   SOLE   220,902 0 0
COGENT BIOSCIENCES INC COM 19240Q201   11,704,477 815,075 SH   SOLE   815,075 0 0
COGENT BIOSCIENCES INC CALL 19240Q901   5,169,600 360,000 SH Call SOLE   360,000 0 0
COMPASS THERAPEUTICS INC COM 20454B104   9,918,958 2,833,988 SH   SOLE   2,833,988 0 0
COMPUGEN LTD ORD M25722105   4,867,413 3,311,165 SH   SOLE   3,311,165 0 0
CONTINEUM THERAPEUTICS INC CL A 21217B100   1,952,392 166,161 SH   SOLE   166,161 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   2,082,500 50,000 SH   SOLE   50,000 0 0
CYTOKINETICS INC COM NEW 23282W605   11,596,560 211,000 SH   SOLE   211,000 0 0
DELCATH SYS INC COM NEW 24661P807   2,186,400 203,386 SH   SOLE   203,386 0 0
DIANTHUS THERAPEUTICS INC COM 252828108   26,559,912 674,966 SH   SOLE   674,966 0 0
DYNE THERAPEUTICS INC COM 26818M108   1,265,000 100,000 SH   SOLE   100,000 0 0
ELUTIA INC CL A COM 05479K106   2,537,949 2,850,987 SH   SOLE   2,850,987 0 0
ENLIVEN THERAPEUTICS INC COM 29337E102   218,517 10,675 SH   SOLE   10,675 0 0
ERASCA INC COM 29479A108   2,982,404 1,368,075 SH   SOLE   1,368,075 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209   3,287,119 230,837 SH   SOLE   230,837 0 0
FRACTYL HEALTH INC COM 35168W103   16,854,000 10,600,000 SH   SOLE   10,600,000 0 0
GOSSAMER BIO INC COM 38341P102   12,568,986 4,779,082 SH   SOLE   4,779,082 0 0
IMMUNOVANT INC COM 45258J102   806,000 50,000 SH   SOLE   50,000 0 0
INSMED INC COM PAR $.01 457669307   29,759,378 206,648 SH   SOLE   206,648 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103   16,605,944 1,363,378 SH   SOLE   1,363,378 0 0
KINIKSA PHARMACEUTICALS INTL ORD SHS CL A G52694109   3,452,375 88,910 SH   SOLE   88,910 0 0
KODIAK SCIENCES INC COM 50015M109   16,370,000 1,000,000 SH   SOLE   1,000,000 0 0
LB PHARMACEUTICALS INC COM SHS 50180M108   1,105,300 70,000 SH   SOLE   70,000 0 0
LEXEO THERAPEUTICS INC COM 52886X107   5,169,977 778,611 SH   SOLE   778,611 0 0
MBX BIOSCIENCES INC COM 55287L101   262,500 15,000 SH   SOLE   15,000 0 0
MERSANA THERAPEUTICS INC COM 59045L205   1,037,015 133,636 SH   SOLE   133,636 0 0
MINERALYS THERAPEUTICS INC COM 603170101   3,033,600 80,000 SH   SOLE   80,000 0 0
MODULAR MED INC COM NEW 60785L207   447,544 639,531 SH   SOLE   639,531 0 0
MONTE ROSA THERAPEUTICS INC COM 61225M102   5,149,520 694,942 SH   SOLE   694,942 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   215,100 30,000 SH   SOLE   30,000 0 0
MOONLAKE IMMUNOTHERAPEUTICS CALL 61559X904   466,050 65,000 SH Call SOLE   65,000 0 0
NEKTAR THERAPEUTICS COM NEW 640268306   20,769 365 SH   SOLE   365 0 0
NUVALENT INC COM 670703107   32,196,504 372,300 SH   SOLE   372,300 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106   9,139,366 933,541 SH   SOLE   933,541 0 0
ORIC PHARMACEUTICALS INC COM 68622P109   23,385,696 1,948,808 SH   SOLE   1,948,808 0 0
PHARVARIS N V COM N69605108   4,588,380 183,903 SH   SOLE   183,903 0 0
PRAXIS PRECISION MEDICINES I COM NEW 74006W207   2,714,130 51,210 SH   SOLE   51,210 0 0
RADIOPHARM THERANOSTICS LTD SPONSORED ADS 75041J101   1,034,481 187,406 SH   SOLE   187,406 0 0
RAPPORT THERAPEUTICS INC COM 75383L102   6,057,196 203,946 SH   SOLE   203,946 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105   37,365,896 369,996 SH   SOLE   369,996 0 0
ROCKET PHARMACEUTICALS INC *W EXP 09/02/202 77313F114   4,109 104,828 SH   SOLE   104,828 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   8,711,181 233,920 SH   SOLE   233,920 0 0
SIONNA THERAPEUTICS INC COM 829401108   3,199,837 108,801 SH   SOLE   108,801 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   7,134,148 463,708 SH   SOLE   463,708 0 0
SYNDAX PHARMACEUTICALS INC CALL 87164F905   769,500 50,000 SH Call SOLE   50,000 0 0
TELA BIO INC COM 872381108   4,146,555 2,782,923 SH   SOLE   2,782,923 0 0
TREVI THERAPEUTICS INC COM 89532M101   5,387,419 588,789 SH   SOLE   588,789 0 0
ULTRAGENYX PHARMACEUTICAL IN CALL 90400D908   15,888,256 528,200 SH Call SOLE   528,200 0 0
ULTRAGENYX PHARMACEUTICAL IN PUT 90400D958   752,000 25,000 SH Put SOLE   25,000 0 0
UNIQURE NV SHS N90064101   26,558,350 455,000 SH   SOLE   455,000 0 0
UNITED THERAPEUTICS CORP DEL PUT 91307C952   25,110,679 59,900 SH Put SOLE   59,900 0 0
UROGEN PHARMA LTD COM M96088105   31,466,796 1,577,283 SH   SOLE   1,577,283 0 0
VAXCYTE INC COM 92243G108   11,322,491 314,339 SH   SOLE   314,339 0 0
VERACYTE INC COM 92337F107   8,094,705 235,791 SH   SOLE   235,791 0 0
VERASTEM INC COM NEW 92337C203   9,207,544 1,042,757 SH   SOLE   1,042,757 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   5,600,204 259,509 SH   SOLE   259,509 0 0
ZURA BIO LTD CLASS A ORD SHS G9TY5A101   3,119,557 720,452 SH   SOLE   720,452 0 0