The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
89BIO INC COM 282559103   20,004,194 2,037,087 SH   SOLE   2,037,087 0 0
AARDVARK THERAPEUTICS INC COM 002942100   3,877,631 286,807 SH   SOLE   286,807 0 0
ABEONA THERAPEUTICS INC COM NEW 00289Y206   5,213,661 917,898 SH   SOLE   917,898 0 0
AKERO THERAPEUTICS INC COM 00973Y108   38,088,955 713,811 SH   SOLE   713,811 0 0
AKERO THERAPEUTICS INC CALL 00973Y908   1,334,000 25,000 SH Call SOLE   25,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   14,938,875 86,552 SH   SOLE   86,552 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   11,644,000 410,000 SH   SOLE   410,000 0 0
BENITEC BIOPHARMA INC COM NEW 08205P209   2,962,838 253,234 SH   SOLE   253,234 0 0
BIODESIX INC COM 09075X108   302,058 1,070,367 SH   SOLE   1,070,367 0 0
CAPRICOR THERAPEUTICS INC PUT 14070B959   1,436,871 144,700 SH Put SOLE   144,700 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   4,038,274 198,441 SH   SOLE   198,441 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   65,700 5,000 SH   SOLE   5,000 0 0
CERUS CORP COM 157085101   3,508,490 2,488,291 SH   SOLE   2,488,291 0 0
CG ONCOLOGY INC COM 156944100   14,066,884 541,034 SH   SOLE   541,034 0 0
CIDARA THERAPEUTICS INC COM NEW 171757206   5,063,064 103,943 SH   SOLE   103,943 0 0
COGENT COMMUNICATIONS HLDGS CALL 19239V902   3,590,000 500,000 SH Call SOLE   500,000 0 0
COMPASS THERAPEUTICS INC COM 20454B104   3,249,431 1,249,781 SH   SOLE   1,249,781 0 0
COMPUGEN LTD ORD M25722105   5,400,305 3,033,879 SH   SOLE   3,033,879 0 0
DELCATH SYS INC COM NEW 24661P807   1,401,154 103,026 SH   SOLE   103,026 0 0
DIANTHUS THERAPEUTICS INC COM 252828108   1,784,866 95,806 SH   SOLE   95,806 0 0
ELUTIA INC CL A COM 05479K106   5,468,134 2,761,684 SH   SOLE   2,761,684 0 0
ENLIVEN THERAPEUTICS INC COM 29337E102   200,600 10,000 SH   SOLE   10,000 0 0
ERASCA INC COM 29479A108   3,263,381 2,569,591 SH   SOLE   2,569,591 0 0
FRACTYL HEALTH INC COM 35168W103   328,196 202,590 SH   SOLE   202,590 0 0
GOSSAMER BIO INC COM 38341P102   6,330,542 5,146,782 SH   SOLE   5,146,782 0 0
HELIX ACQUISITION CORP II CL A ORD SHS G4444H101   6,514,234 613,393 SH   SOLE   613,393 0 0
HIMS & HERS HEALTH INC PUT 433000956   2,492,500 50,000 SH Put SOLE   50,000 0 0
INSMED INC COM PAR $.01 457669307   25,065,398 249,060 SH   SOLE   249,060 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103   20,712,693 1,832,171 SH   SOLE   1,832,171 0 0
KINIKSA PHARMACEUTICALS INTL ORD SHS CL A G52694109   2,101,786 75,959 SH   SOLE   75,959 0 0
KODIAK SCIENCES INC COM 50015M109   1,497,744 401,540 SH   SOLE   401,540 0 0
MERSANA THERAPEUTICS INC COM 59045L106   926,013 3,128,421 SH   SOLE   3,128,421 0 0
MERUS N V COM N5749R100   39,027,727 741,972 SH   SOLE   741,972 0 0
MERUS N V CALL N5749R900   20,119,500 382,500 SH Call SOLE   382,500 0 0
METSERA INC COM 59267L107   5,905,679 207,581 SH   SOLE   207,581 0 0
MINERALYS THERAPEUTICS INC COM 603170101   1,559,765 115,282 SH   SOLE   115,282 0 0
MODULAR MED INC COM NEW 60785L207   529,220 710,363 SH   SOLE   710,363 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   3,871,486 82,023 SH   SOLE   82,023 0 0
NEKTAR THERAPEUTICS COM NEW 640268306   8,941 346 SH   SOLE   346 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109   20,483,574 162,969 SH   SOLE   162,969 0 0
NUVALENT INC COM 670703107   17,974,983 235,583 SH   SOLE   235,583 0 0
NUVALENT INC CALL 670703907   7,645,260 100,200 SH Call SOLE   100,200 0 0
ORIC PHARMACEUTICALS INC COM 68622P109   18,278,414 1,800,829 SH   SOLE   1,800,829 0 0
ORUKA THERAPEUTICS INC COM 687604108   1,854,011 165,389 SH   SOLE   165,389 0 0
PFIZER INC COM 717081103   8,346,753 344,338 SH   SOLE   344,338 0 0
PRAXIS PRECISION MEDICINES I COM NEW 74006W207   420,500 10,000 SH   SOLE   10,000 0 0
RADIOPHARM THERANOSTICS LTD SPONSORED ADS 75041J101   869,564 187,406 SH   SOLE   187,406 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105   25,324,783 400,772 SH   SOLE   400,772 0 0
ROCKET PHARMACEUTICALS INC *W EXP 09/02/202 77313F114   3,019 104,828 SH   SOLE   104,828 0 0
SAGIMET BIOSCIENCES INC COM SER A 786700104   286,047 37,539 SH   SOLE   37,539 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   12,078,574 341,010 SH   SOLE   341,010 0 0
SIONNA THERAPEUTICS INC COM 829401108   3,227,360 186,015 SH   SOLE   186,015 0 0
SOLENO THERAPEUTICS INC COM 834203309   17,140,634 204,591 SH   SOLE   204,591 0 0
SPDR SERIES TRUST CALL 78464A900   16,586,000 200,000 SH Call SOLE   200,000 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   3,642,691 175,636 SH   SOLE   175,636 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   3,773,758 402,964 SH   SOLE   402,964 0 0
SYNDAX PHARMACEUTICALS INC CALL 87164F905   468,000 50,000 SH Call SOLE   50,000 0 0
TELA BIO INC COM 872381108   5,392,802 2,779,795 SH   SOLE   2,779,795 0 0
TOURMALINE BIO INC COM 89157D105   1,747,019 109,257 SH   SOLE   109,257 0 0
TREVI THERAPEUTICS INC COM 89532M101   2,951,541 539,587 SH   SOLE   539,587 0 0
UNIQURE NV SHS N90064101   2,823,756 202,565 SH   SOLE   202,565 0 0
UROGEN PHARMA LTD COM M96088105   27,708,003 2,022,482 SH   SOLE   2,022,482 0 0
VAXCYTE INC COM 92243G108   9,356,248 287,796 SH   SOLE   287,796 0 0
VERACYTE INC COM 92337F107   12,122,820 448,495 SH   SOLE   448,495 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106   33,887,730 358,297 SH   SOLE   358,297 0 0