0001420506-23-000635.txt : 20230214 0001420506-23-000635.hdr.sgml : 20230214 20230214122941 ACCESSION NUMBER: 0001420506-23-000635 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20221231 FILED AS OF DATE: 20230214 DATE AS OF CHANGE: 20230214 EFFECTIVENESS DATE: 20230214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: SILVERARC CAPITAL MANAGEMENT, LLC CENTRAL INDEX KEY: 0001816307 IRS NUMBER: 834542901 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-21010 FILM NUMBER: 23625588 BUSINESS ADDRESS: STREET 1: 20 PARK PLAZA STREET 2: 4TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 BUSINESS PHONE: 617.284.6952 MAIL ADDRESS: STREET 1: 20 PARK PLAZA STREET 2: 4TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false true false 0001816307 XXXXXXXX 12-31-2022 12-31-2022 false SILVERARC CAPITAL MANAGEMENT, LLC

20 PARK PLAZA 4TH FLOOR BOSTON MA 02116

13F HOLDINGS REPORT 028-21010 N ANDREW TIMPSON 617.284.6952 ANDREW TIMPSON, CHIEF COMPLIANCE OFFICER BOSTON MA 02-14-2023 1 90 349550312 false 1 028-20993 SILVERARC CAPITAL, LLC INFORMATION TABLE 2 Form13F_InfoTable.xml INFORMATION TABLE FOR SILVERARC CAPITAL MANAGEMENT, LLC (5788) Aclaris Therapeutics Inc EQUITIES 00461U105 5547040 352193 SH SOLE 352193 0 0 Acumen Pharmaceuticals Inc EQUITIES 00509G209 1593621 295115 SH SOLE 295115 0 0 Aerovate Therapeutics Inc EQUITIES 008064107 1081346 36906 SH SOLE 36906 0 0 Akero Therapeutics Inc LONG OPTION PUTS 00973Y108 8220000 150000 SH Put SOLE 150000 0 0 Akero Therapeutics Inc LONG OPTION CALLS 00973Y108 8220000 150000 SH Call SOLE 150000 0 0 Akero Therapeutics Inc EQUITIES 00973Y108 9431080 172100 SH SOLE 172100 0 0 Allakos Inc EQUITIES 01671P100 4047502 480701 SH SOLE 480701 0 0 Alnylam Pharmaceuticals Inc EQUITIES 02043Q107 8947998 37652 SH SOLE 37652 0 0 Altimmune Inc EQUITIES 02155H200 831482 50546 SH SOLE 50546 0 0 Altimmune, Inc. LONG OPTION CALLS 02155H200 2632000 160000 SH Call SOLE 160000 0 0 Amryt Pharma PLC EQUITIES 03217L106 1408864 192995 SH SOLE 192995 0 0 Anavex Life Science Corp LONG OPTION PUTS 032797300 9331302 1007700 SH Put SOLE 1007700 0 0 Anavex Life Science Corp LONG OPTION CALLS 032797300 950076 102600 SH Call SOLE 102600 0 0 Ascendis Pharma A/S EQUITIES 04351P101 2827432 23151 SH SOLE 23151 0 0 Astria Therapeutics Inc EQUITIES 04635X102 1209128 81204 SH SOLE 81204 0 0 Avidity Biosciences Inc EQUITIES 05370A108 2840320 128000 SH SOLE 128000 0 0 Axsome Therapeutics Inc EQUITIES 05464T104 771300 10000 SH SOLE 10000 0 0 Bellus Health Inc EQUITIES 07987C204 14034581 1707370 SH SOLE 1707370 0 0 BioCryst Pharmaceuticals Inc EQUITIES 09058V103 3124546 272173 SH SOLE 272173 0 0 Bioatla Inc EQUITIES 09077B104 4511719 546875 SH SOLE 546875 0 0 Biogen Idec Inc EQUITIES 09062X103 6085317 21975 SH SOLE 21975 0 0 Braze Inc EQUITIES 10576N102 272800 10000 SH SOLE 10000 0 0 CTI BioPharma Corp EQUITIES 12648L601 1528710 254361 SH SOLE 254361 0 0 Celldex Therapeutics Inc EQUITIES 15117B202 2437934 54699 SH SOLE 54699 0 0 Cerus Corp EQUITIES 157085101 5964151 1634014 SH SOLE 1634014 0 0 Cincor Pharma Inc EQUITIES 17240Y109 4859245 395382 SH SOLE 395382 0 0 Codexis Inc EQUITIES 192005106 674474 144737 SH SOLE 144737 0 0 Cogent Biosciences Inc EQUITIES 19240Q201 2069240 179000 SH SOLE 179000 0 0 Compass Therapeutics Inc. EQUITIES 20454B104 1349584 268307 SH SOLE 268307 0 0 Compugen Ltd EQUITIES M25722105 477689 667443 SH SOLE 667443 0 0 Crinetics Pharmaceuticals Inc EQUITIES 22663K107 2795270 152747 SH SOLE 152747 0 0 Cue Biopharma Inc EQUITIES 22978P106 872892 306278 SH SOLE 306278 0 0 Cullinan Oncology Inc EQUITIES 230031106 2420339 229416 SH SOLE 229416 0 0 Cvrx Inc EQUITIES 126638105 5772616 314584 SH SOLE 314584 0 0 Cytokinetics Inc EQUITIES 23282W605 801850 17500 SH SOLE 17500 0 0 Design Therapeutics Inc EQUITIES 25056L103 585077 57025 SH SOLE 57025 0 0 Eliem Therapeutics Inc EQUITIES 28658R106 1501771 409202 SH SOLE 409202 0 0 Eloxx Pharmaceuticals Inc EQUITIES 29014R202 48914 26876 SH SOLE 26876 0 0 Evogene Ltd EQUITIES M4119S104 105253 150361 SH SOLE 150361 0 0 Fresh Tracks Therapeutics Inc EQUITIES 10802T204 15000 10000 SH SOLE 10000 0 0 Gilead Sciences Inc EQUITIES 375558103 4460938 51962 SH SOLE 51962 0 0 GlaxoSmithKline PLC EQUITIES 37733W204 4785295 136178 SH SOLE 136178 0 0 Gossamer Bio Inc EQUITIES 38341P102 217000 100000 SH SOLE 100000 0 0 Horizon Therapeutics Plc EQUITIES G46188101 2623545 23054 SH SOLE 23054 0 0 IVERIC bio Inc EQUITIES 46583P102 1889283 88243 SH SOLE 88243 0 0 Immatics Nv EQUITIES N44445109 3830553 439788 SH SOLE 439788 0 0 Immunic Inc EQUITIES 4525EP101 490918 350656 SH SOLE 350656 0 0 ImmunoGen Inc EQUITIES 45253H101 2020054 407269 SH SOLE 407269 0 0 ImmunoGen, Inc. LONG OPTION CALLS 45253H101 1150720 232000 SH Call SOLE 232000 0 0 Immunovant Inc EQUITIES 45258J102 9223149 519614 SH SOLE 519614 0 0 Insmed Inc EQUITIES 457669307 2486811 124465 SH SOLE 124465 0 0 Intellia Therapeutics Inc EQUITIES 45826J105 1143345 32770 SH SOLE 32770 0 0 Intra-Cellular Therapies Inc EQUITIES 46116X101 7428169 140366 SH SOLE 140366 0 0 Krystal Biotech Inc EQUITIES 501147102 4637143 58535 SH SOLE 58535 0 0 LAVA Therapeutics NV EQUITIES N51517105 1532167 437762 SH SOLE 437762 0 0 MacroGenics Inc EQUITIES 556099109 4109707 612475 SH SOLE 612475 0 0 Madrigal Parmaceuticals, Inc. LONG OPTION PUTS 558868105 8707500 30000 SH Put SOLE 30000 0 0 Madrigal Pharmaceuticals Inc EQUITIES 558868105 14482895 49898 SH SOLE 49898 0 0 Medicus Sciences Acquisition Corp WARRANTS G5960S124 4499 49990 SH SOLE 49990 0 0 Meiragtx Holdings Plc EQUITIES G59665102 369501 56672 SH SOLE 56672 0 0 Mersana Therapeutics Inc EQUITIES 59045L106 6681467 1140182 SH SOLE 1140182 0 0 Merus NV EQUITIES N5749R100 4249671 274704 SH SOLE 274704 0 0 Morphic Holding Inc EQUITIES 61775R105 8948811 334535 SH SOLE 334535 0 0 Nuvalent Inc EQUITIES 670703107 9022238 302963 SH SOLE 302963 0 0 Oric Pharmaceuticals Inc EQUITIES 68622P109 7281783 1236296 SH SOLE 1236296 0 0 Pharvaris NV EQUITIES N69605108 1125000 100000 SH SOLE 100000 0 0 Phreesia Inc EQUITIES 71944F106 2763220 85390 SH SOLE 85390 0 0 Pliant Therapeutics Inc EQUITIES 729139105 4204333 217503 SH SOLE 217503 0 0 Point Biopharma Global Inc EQUITIES 730541109 2921919 400812 SH SOLE 400812 0 0 Poseida Therapeutics Inc EQUITIES 73730P108 11819000 2230000 SH SOLE 2230000 0 0 Praxis Precision Medicines Inc EQUITIES 74006W108 234213 98409 SH SOLE 98409 0 0 Prometheus Bioscience, Inc. LONG OPTION PUTS 74349U108 18964000 172400 SH Put SOLE 172400 0 0 Prometheus Biosciences Inc EQUITIES 74349U108 5500000 50000 SH SOLE 50000 0 0 Prothena Corporation PLC EQUITIES G72800108 4320287 71706 SH SOLE 71706 0 0 Schrodinger Inc EQUITIES 80810D103 2018520 108000 SH SOLE 108000 0 0 Seagen Inc EQUITIES 81181C104 1415666 11016 SH SOLE 11016 0 0 Seres Therapeutics Inc EQUITIES 81750R102 2096763 374422 SH SOLE 374422 0 0 Stereotaxis Inc EQUITIES 85916J409 734695 354925 SH SOLE 354925 0 0 Terns Pharmaceuticals Inc EQUITIES 880881107 7126000 700000 SH SOLE 700000 0 0 Trevi Therapeutics Inc EQUITIES 89532M101 1481528 767631 SH SOLE 767631 0 0 Uniqure NV EQUITIES N90064101 226700 10000 SH SOLE 10000 0 0 United Therapeutics Corp EQUITIES 91307C102 4462788 16048 SH SOLE 16048 0 0 Vaxcyte Inc EQUITIES 92243G108 3986323 83135 SH SOLE 83135 0 0 Veracyte Inc EQUITIES 92337F107 4746000 200000 SH SOLE 200000 0 0 Vertex Pharmaceuticals Inc EQUITIES 92532F100 3287472 11384 SH SOLE 11384 0 0 Veru Inc. LONG OPTION PUTS 92536C103 924000 175000 SH Put SOLE 175000 0 0 Viewray Inc EQUITIES 92672L107 10776013 2405360 SH SOLE 2405360 0 0 Viridian Therapeutics Inc EQUITIES 92790C104 87630 3000 SH SOLE 3000 0 0 WAVE Life Sciences Ltd EQUITIES Y95308105 350000 50000 SH SOLE 50000 0 0 Xenon Pharmaceuticals Inc EQUITIES 98420N105 10001617 253655 SH SOLE 253655 0 0