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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2024
Income Tax Disclosure [Abstract]  
Schedule of Components of Income Tax Expense (Benefit) The components of the income tax expense (benefit) were as follows (in thousands):
Year Ended December 31,
20242023
Current
Federal$— $(164)
State(15)
Total current(179)
Deferred
Federal— — 
State— — 
Total deferred— — 
Total income tax expense (benefit)$$(179)
Schedule of Effective Income Tax Rate Reconciliation
A reconciliation of the Company’s income tax expense (benefit) to the amount computed by applying the federal statutory income tax rate is summarized as follows (in thousands):
Year Ended December 31,
20242023
Expected tax benefit computed at federal statutory rate$(10,452)$(14,731)
State income taxes, net of federal tax benefit(2,117)(1,153)
Research and development credit carryforwards(2,119)(5,472)
Reserve for uncertain tax positions2,328 1,517 
Prior year permanent differences586 (699)
Current year permanent differences377 120 
Other515 236 
Change in valuation allowance10,883 20,003 
Income tax expense (benefit)$$(179)
Schedule of Deferred Tax Assets and Liabilities
Significant components of the Company’s net deferred tax assets (liabilities) are summarized as follows (in thousands):
Year Ended December 31,
20242023
Deferred tax assets
Net operating loss carryforwards$15,543 $3,975 
Research and development credit carryforwards8,162 6,269 
Capitalized research and development28,294 15,282 
Other1,795 1,284 
Total deferred tax assets53,794 26,810 
Valuation allowance(53,174)(26,736)
Net deferred tax assets620 74 
Deferred tax liabilities
Other(620)(74)
Total deferred tax liabilities620 74 
Net deferred tax assets$— $— 
Summary of Operating Loss Carryforwards and Tax Credit Carryforwards
At December 31, 2024, the Company's federal and state net operating loss (NOL) and tax credit carryforwards were as follows:
AmountExpiration Years
Net operating losses, federal (starting from January 1, 2018)$72,899 Do not expire
Net operating losses, state3,908 
2040 - 2044
Tax credits, federal7,646 
2040 - 2044
Tax credits, state653 2042
Schedule of Unrecognized Tax Benefits Roll Forward
The following table summarizes the changes to the Company’s gross unrecognized tax benefits (in thousands):
Year Ended December 31,
20242023
Balance at beginning of year$1,953 $131 
Increases (decreases) related to prior year tax positions(5)
Increases related to current year tax positions2,334 1,816 
Balance at end of year$4,282 $1,953