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Equity Incentive Plans - Summary of Assumptions under Employee Stock Purchase Plan - Graphite Bio, Inc. (Details) - Graphite Bio, Inc. - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Total $ 10,574 $ 13,534
Restricted stock awards and founders' common stock awards    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Total $ 7 $ 11
Class A common stock options granted and outstanding    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Expected dividend yield 0.00% 0.00%
Expected term 6 years 14 days  
Risk free interest rate, minimum 3.50% 1.91%
Risk free interest rate, maximum 4.12% 4.23%
Total $ 10,471 $ 13,132
Minimum | Class A common stock options granted and outstanding    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Expected volatility, minimum 77.00% 74.00%
Expected term   5 years 11 months 19 days
Maximum | Class A common stock options granted and outstanding    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Expected volatility, maximum 79.00% 75.00%
Expected term   6 years 3 days
2021 Employee Stock Purchase Plan    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Expected dividend yield 0.00% 0.00%
Expected term 6 months 6 months
2021 Employee Stock Purchase Plan | Minimum    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Expected volatility, minimum 75.00% 73.00%
Risk free interest rate, minimum 4.65% 0.10%
2021 Employee Stock Purchase Plan | Maximum    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Expected volatility, maximum 79.00% 75.00%
Risk free interest rate, maximum 5.44% 4.65%
ESPP Shares Available for Future Grants    
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]    
Total $ 96 $ 391