Condensed Statements of Cash Flows (Unaudited) $ in Thousands	3 Months Ended
	Mar. 31, 2022 USD ($)	Mar. 31, 2021 USD ($)
Cash flows from operating activities:
Net loss	$ (25,835)	$ (19,709)
Adjustments to reconcile net loss to net cash used in operations:
Net amortization of premiums and discounts on marketable securities	45
Depreciation and amortization	440	90
Noncash lease expense	1,452
Stock-based compensation expense	3,342	1,033
Change in fair value of the Series A redeemable convertible preferred stock tranche liability		10,341
Changes in assets and liabilities:
Prepaid expenses and other current assets and other assets	(71)	(1,816)
Accounts payable	582	83
Accrued compensation	(1,666)	(179)
Accrued research costs	1,246	1,216
Accrued expenses and other current liabilities and other liabilities	323	881
Operating lease liabilities	(1,098)
Net cash used in operating activities	(21,240)	(8,060)
Cash flows from investing activities:
Purchases of property and equipment	(3,273)	(360)
Purchases of investments in marketable securities	(167,393)
Net cash used in investing activities	(170,666)	(360)
Cash flows from financing activities:
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs		165,632
Payment of deferred offering costs		(133)
Proceeds from issuance of common stock upon exercise of stock options		268
Net cash provided by financing activities		165,767
Net increase in cash, cash equivalents and restricted cash	(191,906)	157,347
Cash, cash equivalents and restricted cash, at beginning of period	378,692	19,817
Cash, cash equivalents and restricted cash, at end of period	186,786	177,164
Reconciliation of cash, cash equivalents and restricted cash to statement of financial position:
Cash and cash equivalents	185,070	177,015
Restricted cash	1,716	149
Cash, cash equivalents and restricted cash, at end of period	186,786	177,164
Supplemental disclosures of non-cash investing and financing information:
Issuance costs of redeemable convertible preferred stock in accrued expenses and accounts payable		111
Purchases of property and equipment included in accounts payable	(109)	(187)
Settlement of redeemable convertible preferred stock tranche liability		(39,403)
Deferred offering costs included in accounts payable and accrued expenses		(595)
Vesting of early exercised stock options	$ 51	$ 7