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Significant Agreements - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Jun. 18, 2021
Jun. 07, 2021
Apr. 30, 2021
Jan. 31, 2021
Dec. 31, 2020
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Dec. 31, 2020
May 07, 2021
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Common stock, shares, issued         10,279,102 58,079,002       58,079,002   10,279,102  
Research and development           $ 8,683,000     $ 2,310,000 $ 26,727,000 $ 2,733,000    
General and administrative           5,919,000     $ 1,454,000 14,776,000 $ 2,444,000    
Share-based compensation arrangement exercised                 236,660   236,660    
Common Stock                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Share-based compensation arrangement exercised               918,825 236,660        
Stanford Exclusive License Agreement                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Upfront license fees received         $ 50,000                
Common stock, shares, issued         600,000             600,000 640,861
Common stock additional paid in capital         $ 2,800,000             $ 2,800,000  
Purchase of shares in private financings percentage         10.00%                
Shares repurchased 624,845                        
Research and development                       2,800,000  
General and administrative                       200,000  
First commercial sale                       50,000  
Subsequent year commercial sale                       200,000  
Maximum future development and regulatory milestones payments                   5,300,000      
Sale-based milestones payments                   7,500,000      
Milestone payments                   $ 0   0  
Stanford Exclusive License Agreement | First Year                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Annual maintenance fees                       5,000  
Stanford Exclusive License Agreement | Second Year                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Annual maintenance fees                       10,000  
Stanford Exclusive License Agreement | Third Year                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Annual maintenance fees                       10,000  
Stanford Exclusive License Agreement | Fourth Year                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Annual maintenance fees                       25,000  
Stanford Exclusive License Agreement | Fifth Year                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Annual maintenance fees                       25,000  
Stanford Exclusive License Agreement | Sixth Year                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Annual maintenance fees                       $ 25,000  
License Agreement with Stanford | Common Stock                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Shares repurchased 624,845           624,845            
First Option Agreement                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Common stock, shares, issued       132,137                  
License execution fee       $ 10,000                  
Option agreement expiration term       18 months                  
Share-based compensation arrangement exercised                   0      
Second Option Agreement                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Share-based compensation arrangement exercised                   0      
Options fee     $ 30,000                    
LCGM Service Agreement                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Research and development           700,000       $ 1,700,000      
Annual fee payable           2,800,000       2,800,000      
IDT License Agreement                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Research and development           0.0       3,000,000.0      
Milestone payments           0       0      
Exercise fee   $ 500,000                      
Upfront payment   3,000,000.0                      
Milestones probable           $ 0       0      
IDT License Agreement | Research and Development Expenses                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Total consideration                   $ 3,000,000.0      
IDT License Agreement | Maximum                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Upfront payment   5,300,000                      
IDT License Agreement | Beta Thalassemia and Lysosomal Storage Disorders Fields                          
Research And Development Arrangement Contract To Perform For Others [Line Items]                          
Exercise fee   1,000,000.0                      
Upfront payment   $ 8,800,000