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Significant Agreements - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Jun. 18, 2021
Jun. 07, 2021
Apr. 30, 2021
Jan. 31, 2021
Dec. 31, 2020
Jun. 30, 2021
Mar. 31, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Dec. 31, 2020
May 07, 2021
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Common stock, shares, issued         10,279,102 55,979,002     55,979,002   10,279,102  
Research and development           $ 12,667,000   $ 423,000 $ 18,044,000 $ 423,000    
General and administrative           $ 4,866,000   $ 869,000 8,857,000 $ 990,000    
Common Stock                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Share-based compensation arrangement exercised           3,383 918,825          
Stanford Exclusive License Agreement                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Upfront license fees received         $ 50,000              
Common stock, shares, issued         600,000           600,000 640,861
Common stock additional paid in capital         $ 2,800,000           $ 2,800,000  
Purchase of shares in private financings percentage         10.00%              
Shares repurchased 624,845                      
Research and development           $ 50,000     50,000   2,800,000  
General and administrative                     200,000  
First commercial sale                     50,000  
Subsequent year commercial sale                     200,000  
Maximum future development and regulatory milestones payments                 5,300,000      
Sale-based milestones payments                 7,500,000      
Milestone payments                 $ 0   0  
Stanford Exclusive License Agreement | First Year                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Annual maintenance fees                     5,000  
Stanford Exclusive License Agreement | Second Year                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Annual maintenance fees                     10,000  
Stanford Exclusive License Agreement | Third Year                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Annual maintenance fees                     10,000  
Stanford Exclusive License Agreement | Fourth Year                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Annual maintenance fees                     25,000  
Stanford Exclusive License Agreement | Fifth Year                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Annual maintenance fees                     25,000  
Stanford Exclusive License Agreement | Sixth Year                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Annual maintenance fees                     $ 25,000  
License Agreement with Stanford | Common Stock                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Shares repurchased 624,845         624,845            
First Option Agreement                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Common stock, shares, issued       132,137                
License execution fee       $ 10,000                
Option agreement expiration term       18 months                
Share-based compensation arrangement exercised                 0      
Second Option Agreement                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Share-based compensation arrangement exercised                 0      
Options fee     $ 30,000                  
IDT License Agreement                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Research and development           $ 3,000,000.0     $ 3,000,000.0      
Milestone payments           0     0      
Exercise fee   $ 500,000                    
Upfront payment   3,000,000.0                    
Milestones probable           0     0      
IDT License Agreement | Research and Development Expenses                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Total consideration           $ 3,000,000.0     $ 3,000,000.0      
IDT License Agreement | Maximum                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Upfront payment   5,300,000                    
IDT License Agreement | Beta Thalassemia and Lysosomal Storage Disorders Fields                        
Research And Development Arrangement Contract To Perform For Others [Line Items]                        
Exercise fee   1,000,000.0                    
Upfront payment   $ 8,800,000