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Condensed Statements of Stockholders' Equity (unaudited) - USD ($)
Total
Initial Public Offering
Series A Redeemable Convertible Preferred Stock
Series A Redeemable Convertible Preferred Stock
Initial Public Offering
Series B Redeemable Convertible Preferred Stock
Series B Redeemable Convertible Preferred Stock
Initial Public Offering
Common Stock
Common Stock
Initial Public Offering
Common Stock
License Agreement with Stanford
Additional Paid in Capital
Additional Paid in Capital
Initial Public Offering
Accumulated Deficit
Accumulated Other Comprehensive Loss
Beginning balance at Dec. 31, 2020 $ (65,408,000)                 $ 5,183,000   $ (70,591,000)  
Temporary equity, Beginning balance, Shares at Dec. 31, 2020     30,019,945                    
Temporary equity, Beginning balance at Dec. 31, 2020     $ 55,608,000                    
Beginning balance, Shares at Dec. 31, 2020             10,279,102            
Common stock issued upon exercise of options 42,000                 42,000      
Common stock issued upon exercise of options, Shares             33,906            
Common stock issued upon early exercise of options, Shares             918,825            
Common stock issued under ESPP 306,000                 306,000      
Common stock issued under ESPP, Shares             39,894            
Issuance of redeemable convertible preferred stock for cash     $ 14,997,000   $ 150,524,000                
Issuance of redeemable convertible preferred stock for cash, Shares     15,000,000   29,792,487                
Reclassification of tranche liability upon settlement     $ 39,403,000                    
Issuance of common stock   $ 251,323,000                 $ 251,323,000    
Issuance of common stock, Shares               16,100,000 640,861        
Repurchase of founders' shares, shares                 624,845        
Conversion of redeemable convertible preferred stock to common stock at closing of initial public offering   $ 260,532,000           $ 1,000     $ 260,531,000    
Temporary equity, Conversion of redeemable convertible preferred stock to common stock at closing of initial public offering, Shares       (45,019,945)   (29,792,487)              
Temporary equity, Conversion of redeemable convertible preferred stock to common stock at closing of initial public offering       $ (110,008,000)   $ (150,524,000)              
Conversion of redeemable convertible preferred stock to common stock at closing of initial public offering, Shares               30,761,676          
Stock-based compensation expense 7,871,000                 7,871,000      
Vesting of early exercised stock options 144,000                 144,000      
Repurchase of unvested early exercised shares, Shares             138,596            
Net loss (70,760,000)                     (70,760,000)  
Ending balance at Dec. 31, 2021 384,050,000           $ 1,000     525,400,000   (141,351,000)  
Ending balance, Shares at Dec. 31, 2021             58,010,823            
Stock-based compensation expense 3,342,000                 3,342,000      
Unrealized gain (loss) on investments in marketable securities (309,000)                       $ (309,000)
Vesting of early exercised stock options 51,000                 51,000      
Net loss (25,835,000)                     (25,835,000)  
Ending balance at Mar. 31, 2022 361,299,000           $ 1,000     528,793,000   (167,186,000) (309,000)
Ending balance, Shares at Mar. 31, 2022             58,010,823            
Beginning balance at Dec. 31, 2021 384,050,000           $ 1,000     525,400,000   (141,351,000)  
Beginning balance, Shares at Dec. 31, 2021             58,010,823            
Net loss (76,453,000)                        
Ending balance at Sep. 30, 2022 316,453,000           $ 1,000     535,852,000   (217,804,000) (1,596,000)
Ending balance, Shares at Sep. 30, 2022             58,149,317            
Beginning balance at Dec. 31, 2021 384,050,000           $ 1,000     525,400,000   (141,351,000)  
Beginning balance, Shares at Dec. 31, 2021             58,010,823            
Common stock issued upon exercise of options 20,000                 20,000      
Common stock issued upon exercise of options, Shares             67,196            
Common stock issued under ESPP 656,000                 656,000      
Common stock issued under ESPP, Shares             333,155            
Stock-based compensation expense 13,534,000                 13,534,000      
Unrealized gain (loss) on investments in marketable securities (1,048,000)                       (1,048,000)
Vesting of early exercised stock options 131,000                 131,000      
Repurchase of unvested early exercised shares, Shares             189,414            
Net loss (101,052,000)                     (101,052,000)  
Ending balance at Dec. 31, 2022 296,291,000           $ 1,000     539,741,000   (242,403,000) (1,048,000)
Ending balance, Shares at Dec. 31, 2022             58,221,760            
Beginning balance at Mar. 31, 2022 361,299,000           $ 1,000     528,793,000   (167,186,000) (309,000)
Beginning balance, Shares at Mar. 31, 2022             58,010,823            
Common stock issued upon exercise of options 13,000                 13,000      
Common stock issued upon exercise of options, Shares             43,945            
Common stock issued under ESPP 414,000                 414,000      
Common stock issued under ESPP, Shares             207,137            
Stock-based compensation expense 3,360,000                 3,360,000      
Unrealized gain (loss) on investments in marketable securities (724)                       (724)
Vesting of early exercised stock options 30,000                 30,000      
Repurchase of unvested early exercised shares, Shares             (50,713)            
Net loss (25,936,000)                     (25,936,000)  
Ending balance at Jun. 30, 2022 338,456,000           $ 1,000     532,610,000   (193,122,000) (1,033,000)
Ending balance, Shares at Jun. 30, 2022             58,211,192            
Common stock issued upon exercise of options 5,000                 5,000      
Common stock issued upon exercise of options, Shares             17,000            
Stock-based compensation expense 3,210,000                 3,210,000      
Unrealized gain (loss) on investments in marketable securities (563)                       (563)
Vesting of early exercised stock options 27,000                 27,000      
Repurchase of unvested early exercised shares, Shares             (78,875)            
Net loss (24,682,000)                     (24,682,000)  
Ending balance at Sep. 30, 2022 316,453,000           $ 1,000     535,852,000   (217,804,000) (1,596,000)
Ending balance, Shares at Sep. 30, 2022             58,149,317            
Beginning balance at Dec. 31, 2022 296,291,000           $ 1,000     539,741,000   (242,403,000) (1,048,000)
Beginning balance, Shares at Dec. 31, 2022             58,221,760            
Stock-based compensation expense 3,263,000                 3,263,000      
Unrealized gain (loss) on investments in marketable securities 579,000                       579,000
Vesting of early exercised stock options 25,000                 25,000      
Repurchase of unvested early exercised shares, Shares             (26,942)            
Net loss (23,934,000)                     (23,934,000)  
Ending balance at Mar. 31, 2023 276,224,000           $ 1,000     543,029,000   (266,337,000) (469,000)
Ending balance, Shares at Mar. 31, 2023             58,194,818            
Beginning balance at Dec. 31, 2022 296,291,000           $ 1,000     539,741,000   (242,403,000) (1,048,000)
Beginning balance, Shares at Dec. 31, 2022             58,221,760            
Net loss (101,733,000)                        
Ending balance at Sep. 30, 2023 204,019,000           $ 1,000     548,249,000   (344,136,000) (95,000)
Ending balance, Shares at Sep. 30, 2023             57,971,910            
Beginning balance at Mar. 31, 2023 276,224,000           $ 1,000     543,029,000   (266,337,000) (469,000)
Beginning balance, Shares at Mar. 31, 2023             58,194,818            
Common stock issued upon exercise of options 18,000                 18,000      
Common stock issued upon exercise of options, Shares             55,047            
Common stock issued under ESPP 157,000                 157,000      
Common stock issued under ESPP, Shares             65,222            
Repurchase of founders' shares, shares             (152,694)            
Stock-based compensation expense 2,845,000                 2,845,000      
Unrealized gain (loss) on investments in marketable securities 198,000                       198,000
Vesting of early exercised stock options 18,000                 18,000      
Repurchase of unvested early exercised shares, Shares             (173,120)            
Net loss (55,314,000)                     (55,314,000)  
Ending balance at Jun. 30, 2023 224,146,000           $ 1,000     546,067,000   (321,651,000) (271,000)
Ending balance, Shares at Jun. 30, 2023             57,989,273            
Common stock issued upon exercise of options 16,000                 16,000      
Common stock issued upon exercise of options, Shares             10,367            
Stock-based compensation expense 2,161,000                 2,161,000      
Unrealized gain (loss) on investments in marketable securities 176,000                       176,000
Vesting of early exercised stock options 5,000                 5,000      
Repurchase of unvested early exercised shares, Shares             (27,730)            
Net loss (22,485,000)                     (22,485,000)  
Ending balance at Sep. 30, 2023 $ 204,019,000           $ 1,000     $ 548,249,000   $ (344,136,000) $ (95,000)
Ending balance, Shares at Sep. 30, 2023             57,971,910