Significant Agreements - Additional Information (Details) - USD ($)					1 Months Ended			3 Months Ended				9 Months Ended		12 Months Ended
	Aug. 04, 2023	Aug. 01, 2023	Jun. 18, 2021	Jun. 07, 2021	Apr. 30, 2021	Jan. 31, 2021	Dec. 31, 2020	Sep. 30, 2023	Jun. 30, 2023	Sep. 30, 2022	Jun. 30, 2022	Sep. 30, 2023	Sep. 30, 2022	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2022	May 07, 2021
Research And Development Arrangement Contract To Perform For Others [Line Items]
Common stock, shares, issued								57,971,910				57,971,910				58,221,760
Research and development								$ 2,384,000		$ 18,302,000		$ 32,136,000	$ 54,325,000
General and administrative								11,294,000		$ 7,852,000		26,372,000	24,563,000
Option agreement fees paid												0
Options fee								0				0
Contingencies Recorded
Common Stock
Research And Development Arrangement Contract To Perform For Others [Line Items]
Common stock shares, repurchase								27,730	152,694	78,875
Common stock issued upon exercise of options								10,367	55,047	17,000	43,945
Stanford Exclusive License Agreement
Research And Development Arrangement Contract To Perform For Others [Line Items]
Upfront license fees received							$ 50,000
Common stock, shares, issued							600,000								600,000		640,861
Common stock additional paid in capital							$ 2,800,000								$ 2,800,000
Purchase of shares in private financings percentage							10.00%
Common stock shares, repurchase			624,845
Research and development															2,800,000
General and administrative															200,000
Annual maintenance fees								$ 0				0
First commercial sale															50,000
Subsequent year commercial sale															200,000
Maximum future development and regulatory milestones payments												5,300,000
Sale-based milestones payments												7,500,000
Milestone payments												0
Stanford Exclusive License Agreement | Patents Fees Member
Research And Development Arrangement Contract To Perform For Others [Line Items]
General and administrative								0				0
Stanford Exclusive License Agreement | First Year
Research And Development Arrangement Contract To Perform For Others [Line Items]
Annual maintenance fees															5,000
Stanford Exclusive License Agreement | Second Year
Research And Development Arrangement Contract To Perform For Others [Line Items]
Annual maintenance fees															10,000
Stanford Exclusive License Agreement | Third Year
Research And Development Arrangement Contract To Perform For Others [Line Items]
Annual maintenance fees															10,000
Stanford Exclusive License Agreement | Fourth Year
Research And Development Arrangement Contract To Perform For Others [Line Items]
Annual maintenance fees															25,000
Stanford Exclusive License Agreement | Fifth Year
Research And Development Arrangement Contract To Perform For Others [Line Items]
Annual maintenance fees															25,000
Stanford Exclusive License Agreement | Sixth Year
Research And Development Arrangement Contract To Perform For Others [Line Items]
Annual maintenance fees															$ 25,000
License Agreement with Stanford | Common Stock
Research And Development Arrangement Contract To Perform For Others [Line Items]
Common stock shares, repurchase			624,845
First Option Agreement
Research And Development Arrangement Contract To Perform For Others [Line Items]
Common stock, shares, issued						132,137
License execution fee						$ 10,000
Option agreement expiration term						18 months
Second Option Agreement
Research And Development Arrangement Contract To Perform For Others [Line Items]
Options fee					$ 30,000
LCGM Service Agreement
Research And Development Arrangement Contract To Perform For Others [Line Items]
Research and development								0		$ 1,700,000		1,100,000	4,500,000
IDT License Agreement
Research And Development Arrangement Contract To Perform For Others [Line Items]
Research and development								0				0
Milestone payments								0		0		0	0
Option agreement fees paid												0
Exercise fee				$ 500,000
Upfront payment				3,000,000
Milestones probable								0		$ 0		0	$ 0
IDT License Agreement | Research and Development Expenses
Research And Development Arrangement Contract To Perform For Others [Line Items]
Total consideration														$ 3,000,000
IDT License Agreement | Maximum
Research And Development Arrangement Contract To Perform For Others [Line Items]
Upfront payment				5,300,000
IDT License Agreement | Beta Thalassemia and Lysosomal Storage Disorders Fields
Research And Development Arrangement Contract To Perform For Others [Line Items]
Exercise fee				1,000,000
Upfront payment				$ 8,800,000
Asset Purchase Agreement (APA)
Research And Development Arrangement Contract To Perform For Others [Line Items]
Milestone payments		$ 1,000,000
Exchange Amount Of Asset		500,000										500,000
Loss on Disposal Other Income												100,000
Contingencies Recorded								$ 0				0
Reimbursement of Research and Development Amount		$ 600,000										$ 600,000
LOA to Acquire Nula-Cel Assets
Research And Development Arrangement Contract To Perform For Others [Line Items]
Equity Interest Outstanding Shares	20.00%
LOA to Acquire Nula-Cel Assets | License And Option Agreement [Member]
Research And Development Arrangement Contract To Perform For Others [Line Items]
Equity Interset	20.00%							20.00%				20.00%