Statements of Redeemable Convertible Preferred Stock and Stockholders' Equity Deficit - USD ($) $ in Thousands	Total	Initial Public Offering	Series A Redeemable Convertible Preferred Stock	Series A Redeemable Convertible Preferred Stock Initial Public Offering	Series B Redeemable Convertible Preferred Stock	Series B Redeemable Convertible Preferred Stock Initial Public Offering	Common Stock	Common Stock License Agreement with Stanford	Common Stock Initial Public Offering	Additional Paid in Capital	Additional Paid in Capital Initial Public Offering	Accumulated Deficit	Accumulated Other Comprehensive Loss
Beginning balance at Dec. 31, 2020	$ (65,408)									$ 5,183		$ (70,591)
Temporary equity, Beginning balance, Shares at Dec. 31, 2020			30,019,945
Temporary equity, Beginning balance at Dec. 31, 2020			$ 55,608
Beginning balance, Shares at Dec. 31, 2020							10,279,102
Common stock issued upon exercise of options	42									42
Common stock issued upon exercise of options, Shares							33,906
Common stock issued upon early exercise of options, Shares							918,825
Common stock issued under ESPP	306									306
Common stock issued under ESPP, Shares							39,894
Issuance of redeemable convertible preferred stock for cash			$ 14,997		$ 150,524
Issuance of redeemable convertible preferred stock for cash, Shares			15,000,000		29,792,487
Reclassification of tranche liability upon settlement			$ 39,403
Issuance of common stock		$ 251,323									$ 251,323
Issuance of common stock, Shares								640,861	16,100,000
Repurchase of common stock in connection with License Agreement with Stanford, Shares								624,845
Conversion of redeemable convertible preferred stock to common stock at closing of initial public offering		$ 260,532							$ 1		$ 260,531
Temporary equity, Conversion of redeemable convertible preferred stock to common stock at closing of initial public offering, Shares				(45,019,945)		(29,792,487)
Temporary equity, Conversion of redeemable convertible preferred stock to common stock at closing of initial public offering				$ (110,008)		$ (150,524)
Conversion of redeemable convertible preferred stock to common stock at closing of initial public offering, Shares									30,761,676
Stock-based compensation expense	7,871									7,871
Vesting of early exercised stock options	144									144
Repurchase of unvested early exercised stock options, Shares							138,596
Net loss and comprehensive loss	(70,760)
Net loss	(70,760)											(70,760)
Ending balance at Dec. 31, 2021	384,050						$ 1			525,400		(141,351)
Ending balance, Shares at Dec. 31, 2021							58,010,823
Common stock issued upon exercise of options	20									20
Common stock issued upon exercise of options, Shares							67,196
Common stock issued under ESPP	656									656
Common stock issued under ESPP, Shares							333,155
Stock-based compensation expense	13,534									13,534
Unrealized loss on investments in marketable securities	(1,048)												$ (1,048)
Vesting of early exercised stock options	131									131
Repurchase of unvested early exercised stock options, Shares							189,414
Net loss and comprehensive loss	(102,100)
Net loss	(101,052)											(101,052)
Ending balance at Dec. 31, 2022	$ 296,291						$ 1			$ 539,741		$ (242,403)	$ (1,048)
Ending balance, Shares at Dec. 31, 2022							58,221,760