Condensed Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
Cash flows from operating activities:
Net loss	$ (76,453)	$ (51,830)
Adjustments to reconcile net loss to net cash used in operating activities:
Net amortization of premiums and discounts on marketable securities	(479)	0
Depreciation and amortization	1,670	404
Noncash lease expense	4,454	356
Stock-based compensation expense	9,912	5,425
Change in fair value of the Series A redeemable convertible preferred stock tranche liability	0	10,341
Changes in assets and liabilities:
Prepaid expenses and other current assets and other assets	(2,437)	(5,002)
Accounts payable	1,275	1,115
Accrued compensation	657	1,193
Accrued research costs	(280)	(34)
Accrued expenses and other current liabilities and other liabilities	399	716
Operating lease liabilities	(4,269)	57
Net cash used in operating activities	(65,551)	(37,259)
Cash flows from investing activities:
Purchases of property and equipment	(5,573)	(4,759)
Proceeds from maturities of marketable securities	90,000	0
Purchases of investments in marketable securities	(339,814)	0
Net cash used in investing activities	(255,387)	(4,759)
Cash flows from financing activities:
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs	0	165,521
Proceeds from initial public offering, net of issuance costs	0	251,323
Proceeds from issuance of common stock upon exercise of vested stock options	18	21
Proceeds from employee stock purchase plan	414	0
Proceeds from issuance of common stock upon early exercises of stock options	0	289
Repurchase of unvested early exercised shares	(79)	0
Net cash provided by financing activities	353	417,154
Net increase (decrease) in cash, cash equivalents and restricted cash	(320,585)	375,136
Cash, cash equivalents and restricted cash, at beginning of period	378,692	19,817
Cash, cash equivalents and restricted cash, at end of period	58,107	394,953
Reconciliation of cash, cash equivalents and restricted cash to statement of financial position:
Cash and cash equivalents	56,391	394,804
Restricted cash	1,716	149
Cash, cash equivalents and restricted cash in statement of financial position	58,107	394,953
Supplemental disclosures of non-cash investing and financing information:
Conversion of redeemable convertible preferred stock to common stock at closing of initial public offering	0	260,532
Purchases of property and equipment included in accounts payable	(319)	(53)
Settlement of redeemable convertible preferred stock tranche liability	0	(39,403)
Additions to right-of-use assets from new operating lease liabilities	0	9,433
Lessor funded lease incentives included in property and equipment	2,616	0
Vesting of early exercised stock options	$ 108	$ 69