X0306 4 2021-01-13 0 0001693011 Inozyme Pharma, Inc. INZY 0001815707 Basso Stephen C/O INOZYME PHARMA, INC. 321 SUMMER STREET SUITE 400 BOSTON MA 02210 0 1 0 0 SVP Finance (PFO) Stock Option (right to buy) 2.77 2021-01-13 4 A 0 41794 0.00 A 2030-04-22 Common Stock 41794 41794 D This option was granted on April 23, 2020, with vesting subject to the satisfaction of performance based vesting criteria. The performance based vesting criteria were satisfied on January 13, 2021 and the shares underlying the option vest in equal monthly installments from April 23, 2020 through April 23, 2024. /s/ Stephen Basso 2021-01-14