144 0001388406 XXXXXXXX LIVE 0001815442 KYMERA THERAPEUTICS INC 001-39460 500 North Beacon Street, 4th Floor Watertown MA 02472 8572855300 JEREMY CHADWICK Officer Common Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza 8th Floor New York NY 10004

115977 9035768.07 81642394 03/23/2026 NASDAQ Common 03/23/2026 Exercise of Stock Options Issuer N 109127 03/23/2026 Cash Common 03/01/2026 Restricted Stock Units Issuer N 6850 03/01/2026 N/A N 10b5-1 Sales for JEREMY CHADWICK

500 North Beacon Street, 4th Floor Watertown MA 02472

Common 03/11/2026 25758 2145673.70 JEREMY CHADWICK

500 North Beacon Street, 4th Floor Watertown MA 02472

Common 03/04/2026 3919 334272.49 JEREMY CHADWICK

500 North Beacon Street, 4th Floor Watertown MA 02472

Common 03/02/2026 2039 181321.64 The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale. The securities to be sold were acquired upon the vesting of restricted stock units during the period of 3/1/2026 through 3/3/2026. 03/23/2026 12/10/2025 /s/ Jeremy G Chadwick